UNC Oncology Clinical Translational Research Training Program

描述（由申请人提供）：在这份修订后的材料中，北卡罗来纳大学教堂山分校（UNC）成人和儿童血液学/肿瘤学部门，放射肿瘤学部门，UNC Lineberger综合癌症中心（UNC- lccc）和胃肠病学和肝脏病学部门提议创建UNC肿瘤学临床/转化研究培训计划（OCT-RTP）。所有四个组成部分都将为拟议的培训计划提供导师和研究资源，除了UNC-LCCC之外的所有组成部分都将提供学者。OCT-RTP每年将招收两名学者。因此，在第一年，该计划将资助两名学者。在第二至第五年，该计划将资助四名学者（两名新学者，两名继续学者）。首席研究员Richard Goldberg博士是血液学/肿瘤学教授兼主任，也是UNC-LCCC临床研究副主任，在肿瘤学临床试验的指导、规划和执行方面拥有丰富的经验。该计划的目标是建立一支积极主动、训练有素的临床医师研究骨干队伍，他们在寻求研究支持方面具有竞争力，并将成为成功的、独立的、以患者为导向的癌症研究人员。OCT-RTP将提供的培训资源包括：Lineberger综合癌症中心、北卡罗来纳癌症医院、北卡罗来纳大学医学院K30临床研究课程和北卡罗来纳大学种族文化和健康成果项目。OCT-RTP的目标是提高以患者为导向的研究的质量和数量，包括临床研究的所有阶段，特别是涉及转化成分的研究。拟议的培训计划的基础将是为每位学者分配高素质的基础科学和临床导师，并由导师整合小组协调指导活动。一个内部咨询委员会，包括来自四个组成部分的高级教师，将选择和监督学者的进展，而一个外部咨询委员会将每年审查该项目。

DESCRIPTION (provided by applicant): In this revised submission, the University of North Carolina at Chapel Hill (UNC) Divisions of Adult and Pediatric Hematology/Oncology, the Department of Radiation Oncology, the UNC Lineberger Comprehensive Cancer Center (UNC-LCCC) and the Division of Gastroenterology and Hepatology propose to create the UNC Oncology Clinical/Translational Research Training Program (OCT-RTP). All four of the components will contribute mentors and research resources to the proposed training program, and all components except UNC-LCCC will contribute scholars. OCT-RTP will admit two scholars per year. Thus, in Year One, the Program will sponsor two scholars. In Years Two - Five, the Program will sponsor four scholars (two new, two continuing). The PI, Dr. Richard Goldberg, is Professor and Chief of Hematology/Oncology and UNC-LCCC Associate Director for Clinical Research and has extensive experience in the direction, planning, and execution of oncology clinical trials. The program's objectives are to establish a highly motivated and rigorously trained cadre of physician clinical researchers who are competitive in seeking research support and who will become successful, independent patient-oriented cancer investigators. Training resources that will be available for the OCT-RTP include: the Lineberger Comprehensive Cancer Center, the North Carolina Cancer Hospital, the UNC School of Medicine K30 Clinical Research Curriculum and the UNC Program on Ethnicity Culture and Health Outcomes. X The goals of the OCT-RTP are to increase the quality and quantity of patient-oriented research, including all phases of clinical research and particularly that involving a translational component. The foundation of the proposed training program will be the participation of highly qualified basic science and clinical mentors assigned to each scholar with mentoring activities coordinated by a mentor integration panel. An internal advisory committee that includes senior faculty from each of the four components will select and monitor the progress of scholars, while an external advisory committee will review the program annually.