Hypoxia is the common pathway to renal failure

缺氧是肾衰竭的常见途径

• 批准号: nhmrc : 606601
• 负责人: Prof Bruce Gardiner
• 金额: $ 33.03万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/hypoxia-common-pathway-renal-failure/83120
• 关键词: Hypoxia; common; pathway; renal; failure

A lack of oxygen in the kidney (hypoxia) is a primary cause of kidney disease, but the mechanisms are not clear. To determine the processes involved, we will take a new approach; combining a mathematical model with studies of kidney oxygen regulation in both normal and diseased kidneys. We will determine the causes of hypoxia in kidney disease, and find out if preventing hypoxia has the potential to be a treatment for kidney disease.

肾脏缺氧（缺氧）是肾脏疾病的主要原因，但其机制尚不清楚。为了确定所涉及的流程，我们将采取一种新的方法；将数学模型与正常和患病肾脏的肾氧调节研究相结合。我们将确定肾脏疾病缺氧的原因，并查明预防缺氧是否有可能成为肾脏疾病的治疗方法。