CELL, MOLECULAR AND ANIMAL CORE

密苏里大学哥伦比亚分校(MU)项目资助(PPG)，AD的细胞模型：脂质和 相关信号通路，是一个全面的研究和培训计划，调查影响 氧化应激和寡聚AP对神经元功能障碍和慢性炎症的影响 表达不同AD表型的细胞和动物模型。行政核心是一把钥匙 这是PPG成功的关键因素。孙燕姿领导的行政核心的总体目标， 博士学位，是通过监督和监督研究项目和核心，为PPG提供凝聚力。 这一努力包括但不限于预算和高成本资源的管理、 协调受邀发言者的访问，组织内部和外部咨询会议 董事会，以及与其他由NIA资助的研究阿尔茨海默病的研究人员的互动 和国家安全局的项目官员。PPG由三个高度集成的项目和两个核心组成。特定的 核心A的目标是：1)协调和监督PPG行政活动；2)促进互动 在PPG研究人员中；3)组织一系列研讨会，重点关注AD和相关主题；4)提供 统计咨询；5)提供设备维修或更换小型设备的应急资金 设备；6)为PPG设计一个网站；7)设立咨询委员会；8)组织全国 以及PPG执行委员会的国际研讨会和会议。除了Partial之外 对人员的支持，对行政核心A的主要支持是由加州大学提供的赠款 密苏里州-哥伦比亚优质基金。MU将提供资金，通过支持以下方式建立新的教育活动 研讨会演讲者访问墨尔本大学校园，组织地方、国家和国际研讨会， 将加强对阿尔茨海默病发病机制的研究，并通过推动创新预防策略 和延缓疾病的发展。

The University of Missouri-Columbia (MU) Program Project Grant (PPG), Cell Models for AD: Lipids and Related Signaling Pathways, is a comprehensive research and training program that investigates the impact of oxidative stress and oligomeric Ap on neuronal dysfunction and chronic inflammation using appropriate cell and animal models that express different phenotypes of AD. The Administrative Core is a key component for the success of the PPG. The overall goal of the Administrative Core, led by Grace Y. Sun, PhD, is to provide cohesiveness to the PPG by overseeing and supervising Research Projects and Cores. This effort includes, but is not limited to, the administration of the budget and high cost resources, the coordination of visits by invited speakers, the organization of meetings for the internal and external advisory boards, and interactions with other NIA- funded investigators conducting research on Alzheimer's disease and NIA Program Officers. The PPG is comprised of three highly integrated projects and two cores. Specific aims for Core A are: 1) Coordinate and oversee the PPG administrative activities; 2) Foster interactions among PPG researchers; 3) Organize a seminar series to focus on AD and related subjects; 4) Provide statistical consultations; 5) Provide emergency funds for equipment repair or replacement of small equipment; 6) Design a website for the PPG; 7) Establish the Advisory Committee; and 8) Organize national and international symposia and meetings of the PPG Executive Committee. With the exception of partial support for personnel, major support for Administrative Core A is through a grant from the University of Missouri-Columbia PRIME Fund. MU will provide funds to establish new educational activities by supporting visits of seminar speakers to the MU campus, by organizing local, national and international symposia that will enhance research on the pathogenesis of AD, and by promoting innovative strategies for the prevention and retardation of disease progression.