The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities

描述（由申请人提供）：少数族裔社区艾滋病毒和艾滋病临床研究布朗倡议汇集了布朗大学内不同学科的多种临床研究优势。这笔赠款将加强布朗的承诺，即在艾滋病毒预防研究的有前途的领域培训下一代临床研究人员，重点是吸毒者、精神疾病患者和惩教环境中的研究。该计划将提供一个支持性环境，并能够培训、培养和指导少数族裔研究人员，重点关注非裔美国人社区。该机构以及首席研究员和项目教员在培训初级教员成为独立临床研究人员方面拥有良好的记录，不仅在艾滋病毒临床研究领域，而且在药物滥用和精神疾病领域，这些都是与艾滋病毒同时发生的流行病。培训环境结合了Lifespan/塔夫茨/布朗/艾滋病研究中心(CFAR)、布朗酒精和成瘾研究中心(CAAS)、米里亚姆医院免疫学中心和Lifespan/Brown药物滥用治疗中心，为培养博士后研究人员和初级教员提供了一个独特的环境，使他们能够在艾滋病毒、药物滥用和精神疾病相关的临床研究领域获得独立的资助。该计划的关键组成部分包括教学培训和建立导师与学员关系。每年将有五名学员启动该计划。每位学员参与该计划都涉及为期两年的承诺。这包括通过布朗大学临床研究夏季项目进行的第一个夏季教学培训、学员与布朗大学导师的配对以及独立研究项目的开发。围绕研究项目的指导将在第一年进行，随后在第二个夏天进行为期六周的独立研究和强化指导体验。预计第二年的持续指导将导致提交摘要、手稿和 R03/R21/K 奖 NIH 拨款提案。该计划将纳入为受艾滋病毒严重影响的人群提供服务的四个杰出的临床研究中心（罗德岛惩教署、米里亚姆医院免疫学中心、SSTAR 药物滥用治疗计划和罗德岛医院药物滥用研究中心），为学员提供了解如何在成功的临床中心实施想法和假设的机会。

DESCRIPTION (provided by applicant): The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities pulls together multiple clinical research strengths from different disciplines within Brown University. The grant will strengthen Brown's commitment to train the next generation of clinical research investigators in the promising area of HIV prevention research, with an emphasis on substance users, those with mental illness, and research in the correctional setting. This program will provide a supportive environment and be able to train, nurture, and mentor minority researchers with a focus on the African American community. The institution, as well as the Principal Investigator and program faculty, have a robust record of training junior faculty members to be independent clinical investigators, not only in the area of HIV clinical research, but also in the area of substance abuse and mental illness, which are co-occurring epidemics with HIV. The combination of the training environment, which incorporates the Lifespan/Tufts/Brown/ Center for AIDS Research (CFAR), the Brown Center for Alcohol and Addiction Studies (CAAS), The Miriam Hospital Immunology Center, and the Lifespan/Brown Substance Abuse Treatment Unit, provides a unique environment for the nurturing and fostering of postdoctoral researchers and junior faculty members to attain independent funding in the areas of clinical research related to HIV, substance use, and mental illness. Key components of this initiative include didactic training and establishment of a mentor-mentee relationship. Five trainees will initiate the program each year. Each trainee's participation in the program involves a two-year commitment. This includes a first summer of didactic training through the Brown University Summer Program in Clinical Research, the pairing of trainees with Brown University mentors, and the development of an independent research project. Mentoring surrounding the research project will take place over the course of the first year, followed by a six-week independent study and intensive mentoring experience during a second summer. It is expected that continued mentorship throughout the second year will lead to the submission of abstract(s), manuscript(s), and an R03/R21/K award NIH grant proposal. Four outstanding clinical research sites, which serve populations heavily impacted by HIV will be incorporated in this program (the Rhode Island Department of Corrections, The Miriam Hospital Immunology Center, SSTAR Substance Abuse Treatment Program, and the Substance Abuse Research Unit at Rhode Island Hospital), providing trainees with the opportunity to understand how ideas and hypotheses can be implemented at successful clinical sites.