The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities

描述（由申请人提供）：布朗倡议在艾滋病毒和艾滋病临床研究少数民族社区汇集了来自布朗大学不同学科的多个临床研究优势。这笔赠款将加强布朗的承诺，培训下一代临床研究调查人员在艾滋病毒预防研究的有前途的领域，重点是物质使用者，那些有精神疾病，并在矫正环境的研究。该计划将提供一个支持性的环境，并能够培训，培养和指导少数民族研究人员，重点是非洲裔美国人社区。该机构，以及首席研究员和项目教师，有培训初级教师成为独立的临床研究人员，不仅在艾滋病毒临床研究领域，而且在药物滥用和精神疾病领域，这是共同发生的流行病与艾滋病毒的强有力的记录。培训环境的组合，其中包括生命/塔夫茨/布朗/艾滋病研究中心（CFAR），布朗酒精和成瘾研究中心（CAAS），米里亚姆医院免疫学中心，和生命/布朗药物滥用治疗单位，为培养和培养博士后研究人员和初级教师提供了一个独特的环境，以获得临床领域的独立资助。与艾滋病毒、物质使用和精神疾病有关的研究。这一举措的主要组成部分包括教学培训和建立导师-学员关系。每年将有五名受训人员启动该方案。每个受训者参加该方案的时间为两年。这包括通过布朗大学夏季临床研究计划进行的第一个夏季教学培训，学员与布朗大学导师的配对，以及独立研究项目的开发。围绕研究项目的指导将在第一年进行，然后在第二个夏天进行为期六周的独立学习和密集的指导经验。预计整个第二年的持续指导将导致提交摘要，手稿和R 03/R21/K奖NIH资助提案。四个杰出的临床研究站点，服务于受艾滋病毒严重影响的人群将被纳入该计划（罗得岛惩教部，米里亚姆医院免疫学中心，SSTAR药物滥用治疗计划，以及罗得岛医院的药物滥用研究单位），为学员提供机会，了解如何在成功的临床站点实施的想法和假设。

DESCRIPTION (provided by applicant): The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities pulls together multiple clinical research strengths from different disciplines within Brown University. The grant will strengthen Brown's commitment to train the next generation of clinical research investigators in the promising area of HIV prevention research, with an emphasis on substance users, those with mental illness, and research in the correctional setting. This program will provide a supportive environment and be able to train, nurture, and mentor minority researchers with a focus on the African American community. The institution, as well as the Principal Investigator and program faculty, have a robust record of training junior faculty members to be independent clinical investigators, not only in the area of HIV clinical research, but also in the area of substance abuse and mental illness, which are co-occurring epidemics with HIV. The combination of the training environment, which incorporates the Lifespan/Tufts/Brown/ Center for AIDS Research (CFAR), the Brown Center for Alcohol and Addiction Studies (CAAS), The Miriam Hospital Immunology Center, and the Lifespan/Brown Substance Abuse Treatment Unit, provides a unique environment for the nurturing and fostering of postdoctoral researchers and junior faculty members to attain independent funding in the areas of clinical research related to HIV, substance use, and mental illness. Key components of this initiative include didactic training and establishment of a mentor-mentee relationship. Five trainees will initiate the program each year. Each trainee's participation in the program involves a two-year commitment. This includes a first summer of didactic training through the Brown University Summer Program in Clinical Research, the pairing of trainees with Brown University mentors, and the development of an independent research project. Mentoring surrounding the research project will take place over the course of the first year, followed by a six-week independent study and intensive mentoring experience during a second summer. It is expected that continued mentorship throughout the second year will lead to the submission of abstract(s), manuscript(s), and an R03/R21/K award NIH grant proposal. Four outstanding clinical research sites, which serve populations heavily impacted by HIV will be incorporated in this program (the Rhode Island Department of Corrections, The Miriam Hospital Immunology Center, SSTAR Substance Abuse Treatment Program, and the Substance Abuse Research Unit at Rhode Island Hospital), providing trainees with the opportunity to understand how ideas and hypotheses can be implemented at successful clinical sites.