The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities

描述（由申请人提供）：布朗倡议在少数族裔社区的艾滋病毒和艾滋病临床研究汇集了布朗大学不同学科的多个临床研究优势。这笔拨款将加强布朗大学在艾滋病预防研究这一前景广阔的领域培养下一代临床研究人员的承诺，重点是药物使用者、精神疾病患者和惩教机构的研究。该项目将提供一个支持性的环境，并能够培训、培养和指导以非洲裔美国人社区为重点的少数民族研究人员。该机构，以及首席研究员和项目教员，在培训初级教员成为独立临床研究者方面有着良好的记录，不仅在艾滋病毒临床研究领域，而且在药物滥用和精神疾病领域，这是与艾滋病毒共同发生的流行病。培训环境的结合，包括生命/塔夫茨/布朗/艾滋病研究中心（CFAR）、布朗酒精和成瘾研究中心（CAAS）、米里亚姆医院免疫学中心和生命/布朗药物滥用治疗单位，为培养博士后研究人员和初级教员提供了一个独特的环境，以获得与艾滋病毒、药物使用、还有精神疾病。这一倡议的关键组成部分包括教学培训和建立师徒关系。每年将有5名学员启动该项目。每个学员参加这个项目需要两年的承诺。这包括通过布朗大学临床研究暑期项目进行的第一个夏季教学培训，实习生与布朗大学导师的配对，以及独立研究项目的发展。围绕研究项目的指导将在第一年进行，随后是为期六周的独立学习和第二年夏天的强化指导体验。预计在整个第二年继续指导将导致提交摘要，手稿和R03/R21/K奖NIH拨款提案。四个杰出的临床研究机构，服务于受艾滋病毒严重影响的人群，将被纳入该计划（罗德岛惩教部门，米里亚姆医院免疫学中心，SSTAR药物滥用治疗计划和罗德岛医院药物滥用研究部门），为学员提供机会了解如何在成功的临床场所实施想法和假设。

DESCRIPTION (provided by applicant): The Brown Initiative in HIV and AIDS Clinical Research for Minority Communities pulls together multiple clinical research strengths from different disciplines within Brown University. The grant will strengthen Brown's commitment to train the next generation of clinical research investigators in the promising area of HIV prevention research, with an emphasis on substance users, those with mental illness, and research in the correctional setting. This program will provide a supportive environment and be able to train, nurture, and mentor minority researchers with a focus on the African American community. The institution, as well as the Principal Investigator and program faculty, have a robust record of training junior faculty members to be independent clinical investigators, not only in the area of HIV clinical research, but also in the area of substance abuse and mental illness, which are co-occurring epidemics with HIV. The combination of the training environment, which incorporates the Lifespan/Tufts/Brown/ Center for AIDS Research (CFAR), the Brown Center for Alcohol and Addiction Studies (CAAS), The Miriam Hospital Immunology Center, and the Lifespan/Brown Substance Abuse Treatment Unit, provides a unique environment for the nurturing and fostering of postdoctoral researchers and junior faculty members to attain independent funding in the areas of clinical research related to HIV, substance use, and mental illness. Key components of this initiative include didactic training and establishment of a mentor-mentee relationship. Five trainees will initiate the program each year. Each trainee's participation in the program involves a two-year commitment. This includes a first summer of didactic training through the Brown University Summer Program in Clinical Research, the pairing of trainees with Brown University mentors, and the development of an independent research project. Mentoring surrounding the research project will take place over the course of the first year, followed by a six-week independent study and intensive mentoring experience during a second summer. It is expected that continued mentorship throughout the second year will lead to the submission of abstract(s), manuscript(s), and an R03/R21/K award NIH grant proposal. Four outstanding clinical research sites, which serve populations heavily impacted by HIV will be incorporated in this program (the Rhode Island Department of Corrections, The Miriam Hospital Immunology Center, SSTAR Substance Abuse Treatment Program, and the Substance Abuse Research Unit at Rhode Island Hospital), providing trainees with the opportunity to understand how ideas and hypotheses can be implemented at successful clinical sites.