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HIV Prevention for the Mentally Ill: Motivation-Skills

精神病患者的艾滋病毒预防：动机技能

基本信息

批准号：
7346925
负责人：
STEPHEN MICHAEL BRADY
金额：
$ 7.82万
依托单位：
BOSTON MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-02-01 至 2009-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7346925
关键词：
AIDS prevention AIDS/HIV problem Address Adult Affective Age Alcohol or Other Drugs use Appendix Attention Behavior Caring Characteristics Client Clinical Clinical Research Clinical Trials Color Communication Consent Consult Counseling Data Data Analyses Development Drug usage Enrollment Ensure Ethnic Origin Feedback Focus Groups Gender Grant HIV HIV Infections HIV diagnosis Health Services Accessibility Health behavior change Human immunodeficiency virus test Impaired cognition Incidence Individual Intention Intervention Interview Judgment Knowledge Long-Term Effects Manuals Mediation Medical Mental Health Services Mental disorders Mentally Ill Persons Methods Modification Motivation Numbers Outcome Participant Patients Phase Pilot Projects Population Population Intervention Procedures Process Program Description Protocols documentation Provider Psychiatric Diagnosis Psychiatric therapeutic procedure Public Health Randomized Range Rate Recruitment Activity Research Research Personnel Research Project Grants Risk Risk Behaviors Risk Reduction Running Sampling Services Sexually Transmitted Diseases Social Work Socioeconomic Status Standards of Weights and Measures System Target Populations Techniques Testing Time Vulnerable Populations Woman Work base behavioral/social science caN protocol cohort condoms design didesipramine expectation follow-up improved innovation insight interest member men motivational enhancement therapy novel programs psychologic response severe mental illness skills success therapy design therapy development trend

项目摘要

DESCRIPTION (provided by applicant): People with serious mental illness (SMI) continue to be at high risk for HIV infection. Interventions designed to reduce this risk have been met with only modest success, suggesting a critical need for innovative approaches for this population. The proposed R34 exploratory study grant (a revision of an earlier application) will allow us to adapt and refine two manualized interventions for HIV risk reduction for people with SMI. Our primary aim is to develop a "real world" approach towards reducing HIV risk for this population, integrating recent advances in Motivational Interviewing and traditional Skills-Building interventions. Specifically, we will adapt existing HIV risk reduction Skills Building interventions, which have traditionally been administered in group formats, for use with individual patients. We will then incorporate Motivational Interviewing techniques into the Skills-Building intervention so that we will be able to compare the efficacy of each intervention (Skills-Building alone vs. an integrated Skills-Building and Motivational Interviewing intervention) in order to explore the degree to which integration of Motivational Interviewing techniques augment traditional Skills-Building interventions. Development of these interventions will be a central focus of this project, utilizing focus groups and advisory boards consisting of consumers and providers. Following the development phase of the project, we will pilot-test these interventions with an urban and disenfranchised sample of approximately 40 HIV-seropositive and seronegative men and women with serious mental illness, most of whom will be people of color. Participants will be randomly assigned to a brief, integrated Skills-Building-Motivational Interviewing intervention or to a standard Skills-Building intervention of the same duration and number of sessions. The degree to which these interventions are efficacious in reducing HIV risk behaviors and increasing skills in communication/negotiation and correct condom usage will also be examined. Participant characteristics most likely to predict outcome will also be identified. Another key and unique objective for this project is to examine the degree to which these interventions can be useful in facilitating HIV counseling and testing for people with SMI at risk for HIV. It is our expectation that this intervention refinement and pilot testing will provide us with the data and insight needed for a compelling larger-scale clinical trial, which we will pursue through the R01 mechanism.

描述（由申请人提供）：患有严重精神疾病（SMI）的人仍然是感染艾滋病毒的高风险人群。旨在降低这一风险的干预措施仅取得了有限的成功，这表明迫切需要为这一人群采取创新方法。拟议的R34探索性研究拨款（对早期申请的修订）将使我们能够适应和完善两种人为干预措施，以降低重度精神障碍患者的艾滋病毒风险。我们的主要目标是开发一种“现实世界”的方法，结合动机访谈和传统技能建设干预措施的最新进展，降低这一人群的艾滋病毒风险。具体而言，我们将调整现有的降低艾滋病毒风险技能建设干预措施，这些干预措施传统上以小组形式进行管理，用于个体患者。然后，我们将动机性访谈技术纳入技能建设干预，以便我们能够比较每种干预的效果（单独的技能建设与综合的技能建设和动机性访谈干预），以探索动机性访谈技术的整合在多大程度上增强了传统的技能建设干预。制定这些干预措施将是该项目的中心重点，利用由消费者和提供者组成的焦点小组和咨询委员会。在项目的开发阶段之后，我们将对这些干预措施进行试点测试，其中包括大约40名患有严重精神疾病的艾滋病毒血清阳性和血清阴性的城市和被剥夺权利的男性和女性样本，其中大多数是有色人种。参与者将被随机分配到一个简短的、综合的技能建设动机访谈干预或一个标准的技能建设干预，其持续时间和会话数量相同。还将审查这些干预措施在减少艾滋病毒风险行为和提高沟通/谈判技能和正确使用避孕套方面的有效程度。参与者最可能预测结果的特征也将被确定。这个项目的另一个关键和独特的目标是检查这些干预措施在多大程度上有助于为有感染艾滋病毒风险的重度精神障碍患者提供艾滋病毒咨询和检测。我们期望，这种干预改进和试点测试将为我们提供所需的数据和见解，以进行令人信服的大规模临床试验，我们将通过R01机制继续进行。