CORE--MOUSE MODELS
CORE--MOUSE MODELS
批准号:
7455092
负责人:
ALAN S VERKMAN
金额:
$8.75万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-07-01 至 2010-06-30
中文摘要
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英文摘要
The Mouse models Core will carry out breeding and genotype analysis of mice for evaluation of
small-molecule CF therapies and for analysis of small-molecule pharmacology. Wildtype and
homozygous CF mice (AF508, G551D, null) with defined genetic background will be generated.
The Mouse models Core will also carry out potential difference (PD) measurements, and
pharmacokinetic analysis of lead compounds. Wildtype mice will be provided to investigators in
nine projects, and various CF mice in five projects. PD measurements (nasal, rectal, ocular) will be used by two projects, and pharmacology studies will be done for seven projects.
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会议论文
Urea transport inhibitors as a new class of diuretics
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批准号:9248354
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项目类别:
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资助金额:$34.28万
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财政年份:2014
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负责人:ALAN S VERKMAN
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依托单位:
Urea transport inhibitors as a new class of diuretics
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批准号:8666579
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项目类别:
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资助金额:$35.59万
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财政年份:2014
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负责人:ALAN S VERKMAN
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依托单位:
Urea transport inhibitors as a new class of diuretics
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批准号:8816096
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项目类别:
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资助金额:$34.26万
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财政年份:2014
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负责人:ALAN S VERKMAN
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依托单位:
Application of Novel Optical Methods to Cell Dynamics
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批准号:8451997
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项目类别:
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资助金额:$40.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Application of Novel Optical Methods to Cell Dynamics
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批准号:8642647
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项目类别:
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资助金额:$41.21万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Application of Novel Optical Methods to Cell Dynamics
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批准号:8210242
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项目类别:
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资助金额:$46.69万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Admin Core Verkman
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批准号:8564913
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Core A Verkman Screening Core
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批准号:8564917
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Core C finkbeiner Cell Models Core
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批准号:8564919
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Application of Novel Optical Methods to Cell Dynamics
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批准号:8827336
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项目类别:
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资助金额:$41.64万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Composite budget Verkman
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批准号:8564908
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Core D Kurth Synthesis Core
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批准号:8564921
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项目类别:
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资助金额:$16.06万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Core E Haggie Bioassays Core
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批准号:8564923
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Core B Nielson Clinical Materials Core
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批准号:8564918
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项目类别:
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资助金额:$16.07万
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财政年份:2012
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负责人:ALAN S VERKMAN
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依托单位:
Novel small-molecule therapies for CF
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批准号:8110180
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项目类别:
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资助金额:$21.59万
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财政年份:2010
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负责人:ALAN S VERKMAN
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依托单位:
CFTR inhibitors for therapy of polycystic kidney disease
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批准号:7812584
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项目类别:
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资助金额:$49.05万
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财政年份:2009
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负责人:ALAN S VERKMAN
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依托单位:
CFTR inhibitors for therapy of polycystic kidney disease
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批准号:7938623
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项目类别:
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资助金额:$49.87万
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财政年份:2009
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负责人:ALAN S VERKMAN
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依托单位:
Pilot 2
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批准号:7509427
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项目类别:
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资助金额:$7.94万
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财政年份:2007
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负责人:ALAN S VERKMAN
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依托单位:
Administrative Core
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批准号:7501061
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项目类别:
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资助金额:$12.06万
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财政年份:2007
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负责人:ALAN S VERKMAN
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依托单位:
CORE--HIGH-THROUGHPUT SCREENING
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批准号:7455089
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项目类别:
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资助金额:$18.39万
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财政年份:2007
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负责人:ALAN S VERKMAN
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依托单位:
海外基金