MOLECULAR BIOLOGY-BIOCHEMISTRY MODULE

分子生物学-生物化学模块

• 批准号: 7286508
• 负责人: MAUREEN E NEITZ
• 金额: $ 16.73万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7286508
• 关键词: Advisory Committees; Biochemical; Biochemistry; Clinical Research; Faculty; Human; Human Subject Research; Methods; Molecular; Molecular Biology; Names; Participant; Patients; Procedures; Protocols documentation; Records; Recruitment Activity; Research; Research Personnel; Resources; Sampling; Technology; Time; genetic analysis; human subject; instrument; response

The functions of this Module have evolved over the years in response to changing technology and therefore the changing needs of our group. The Module was originally established as a Biochemistry Module. Three cycles ago when molecular methods came into widespread use, a molecular biology component was added making it the Biochemistry-Molecular Biology Module. Now the order of "Molecular Biology" and "Biochemistry" in the Module name has been reversed to reflect that the use of molecular methods is currently the major activity of the Module. The Module does, however, continue to provide the biochemistry resources that are needed by the participating faculty. This is one of our most heavily used Modules. Its major functions are to provide shared-use instruments for molecular and biochemical analyses that are well maintained and accessible, and to provide skilled technical support to perform a variety of commonly used protocols. There is also an important instructional component to the Module: the Module directors help Core participants develop molecular approaches for answering their research questions, and together the Module directors and technician instruct investigators and their staff in the practical aspects of the experimental procedures and instrument use. In response to the expanding use of the Module for genetic analysis of human samples, we plan to add a part time clinical research coordinator to the Module staff. Access to help with human subjects research was identified by the Core Advisory Committee as the most pressing new staffing need in our Core Modules. With the addition of a clinical research coordinator, this Module will therefore be able to assist investigators with drafting human subjects protocols and with all aspects of recruiting subjects, obtaining samples, and managing patient records.

该模块的功能在多年来不断演变，以响应 不断变化的技术，因此也就是我们集团不断变化的需求。该模块最初是作为一个 生物化学舱。三个周期前，当分子方法开始广泛使用时，一种分子生物学 添加了组件，使其成为生物化学-分子生物学模块。现在是“分子”的顺序 模块名称中的“生物学”和“生物化学”已颠倒过来，以反映分子方法的使用 目前，该单元的主要活动。然而，该模块确实继续提供生物化学 参与教职员工所需的资源。 这是我们使用最多的模块之一。其主要功能是为以下方面提供共享使用的工具 维护良好、易于使用的分子和生化分析，并提供熟练的技术支持 支持执行各种常用协议。还有一个重要的教学组成部分 模块：模块主任帮助核心参与者开发分子方法来回答他们的 研究问题，模块主任和技术人员一起指导调查人员及其工作人员 实践性方面的实验程序和仪器使用。 随着人类样本基因分析模块的使用范围不断扩大，我们计划增加一项 兼职临床研究协调员给模块工作人员。获得人类受试者研究帮助的途径是 被核心咨询委员会确定为我们核心模块最紧迫的新人员配置需求。与 因此，增加一名临床研究协调员，该单元将能够协助调查人员起草 人体受试者协议以及招募受试者、获取样本和管理患者的方方面面 唱片。