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Tone acquisition in young children with cochlear implants

植入人工耳蜗的幼儿的音调习得

基本信息

批准号：
7456161
负责人：
LI XU
金额：
$ 22.05万
依托单位：
OHIO UNIVERSITY ATHENS
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-05-13 至 2012-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7456161
关键词：
18 year old Academic Research Enhancement Awards Acoustics Adult Age Age-Years Biological Neural Networks Categories Child China Chinese People Clinical Research Cochlear Implants Cochlear implant procedure Complex Data Data Set Databases Development Education Evaluation Frequencies Hearing Hearing Impaired Persons Implant Judgment Knowledge Laboratories Language Learning Measures Music Numbers Ohio Outcome Measure Pathway Analysis Patients Pattern Perception Performance Population Production Public Health Purpose Quality of life Recruitment Activity Regression Analysis Rehabilitation therapy Research Research Design Sampling Schools Science Sensorineural Hearing Loss Speech Students Testing Thinking Time Universities Week Work age effect base data acquisition design follow-up hearing impairment implantation improved lexical normal aging programs prospective sound speech recognition

项目摘要

DESCRIPTION (provided by applicant): Cochlear implant has helped thousands of patients with profound sensorineural hearing loss to gain hearing and speech recognition. In current designs of cochlear implants, however, pitch information of complex sounds is limited. This imposes a special challenge for patients who speak tone languages, such as Mandarin Chinese. The purpose of the proposed study is to investigate tone acquisition in the increasing number of Mandarin-speaking children with cochlear implants using a prospective, longitudinal research design. Since there are only scarce normative data on Mandarin tone acquisition, we will first establish a database to which the tone acquisition data from children with cochlear implants can be compared. In Specific Aim 1 of the proposed study, 30 normal-hearing, native Mandarin-speaking children will be recruited at age of 6 months and followed up till 3 years of age. The speech samples will be recorded at intervals of 4 - 6 weeks in the period of 2.5 years. In Specific Aim 2, 30 native Mandarin-speaking children (1 - 18 years old) with cochlear implants will be recruited and the speech samples will be recorded at intervals of 4 - 6 weeks from 6 months to 3 years after activation. Both groups of subjects will be recruited from Beijing, China. The recorded speech materials will be subject to acoustic, neural-network, and perceptual analyses that we developed previously. The acoustic analysis will focus on the fundamental frequencies (F0) of the speech tokens, especially the onset and offset F0 values. The neural network analysis will be used to provide an objective measure of tone production accuracy. The perceptual tests in which normal-hearing, native Mandarin-speaking adults (N= 10) will perform tone recognition on the syllables produced by the children will provide a subjective measure of tone production accuracy. To construct the developmental trajectories of tone acquisition, the longitudinal outcome measures of tone production will be plotted as a function of age for the normal-hearing children or duration of implant use for the children with cochlear implants. Multiple regression analyses will be performed to identify any associations of age at implantation and duration of implant use with the tone production measures. Although the proposed study is primarily concerned with lexical tone production, it has important implications for speakers of non-tonal languages. A better representation of pitch information would be useful in identifying and separating multiple talkers and providing music perception for cochlear-implant users. Therefore, the proposed study could improve quality of life for many cochlear implant users. PUBLIC HEALTH RELEVANCE Cochlear implants provide good speech recognition to patients with profound hearing loss but fail to deliver pitch information to the users. The proposed study will carry out a longitudinal evaluation of tone production in prelingually-deaf children who have received cochlear implants and will determine how tone develops with such insufficient pitch information. This research will advance our knowledge of tone development and enhance rehabilitation of cochlear implant users.

描述（由申请人提供）：Cobalar植入物已帮助数千名重度感音神经性听力损失患者获得听力和语言识别。然而，在耳蜗植入物的当前设计中，复杂声音的音高信息是有限的。这对于说普通话等声调语言的患者来说是一个特殊的挑战。本研究采用前瞻性、纵向研究设计，旨在探讨越来越多的普通话儿童人工耳蜗植入后的声调习得情况。由于汉语声调习得的规范性数据很少，我们将首先建立一个数据库，与人工耳蜗植入儿童的声调习得数据进行比较。在拟议研究的具体目标1中，将招募30名听力正常、母语为普通话的儿童，年龄为6个月，并随访至3岁。在2.5年的时间里，每隔4 - 6周记录一次语音样本。在具体目标2中，将招募30名使用人工耳蜗的母语普通话儿童（1 - 18岁），并在激活后6个月至3年内每隔4 - 6周记录一次语音样本。两组受试者均将从中国北京招募。录制的语音材料将受到声学，神经网络和感知分析，我们以前开发的。声学分析将集中于语音标记的基频（F0），特别是起始和偏移F0值。神经网络分析将用于提供音调产生准确性的客观测量。听觉正常、母语为普通话的成年人（N= 10）将对儿童产生的音节进行音调识别的感知测试将提供音调产生准确性的主观测量。为了构建音调获得的发展轨迹，将音调产生的纵向结果测量绘制为听力正常儿童的年龄或人工耳蜗植入儿童的植入物使用持续时间的函数。将进行多元回归分析，以确定植入时年龄和植入物使用持续时间与音调产生测量的任何相关性。虽然这项研究主要关注词汇声调的产生，但它对非声调语言的使用者有重要的意义。音高信息的更好表示将有助于识别和分离多个说话者，并为耳蜗植入用户提供音乐感知。因此，拟议的研究可以改善许多人工耳蜗使用者的生活质量。公共卫生相关性Cochanar植入物为重度听力损失患者提供了良好的语音识别，但无法向用户提供音高信息。拟议的研究将进行一个纵向评估的音生产在prelingually-dealed儿童谁已收到人工耳蜗植入，并将确定如何音调发展与这样的音高信息不足。这项研究将促进我们对音调发展的认识，并促进人工耳蜗使用者的康复。