ARNMD 87th Annual Conference: Disorders of Consciousness

ARNMD 第 87 届年会：意识障碍

• 批准号: 7408693
• 负责人: Jack David Barchas
• 金额: $ 1.3万
• 依托单位: ASSOCIATION FOR RESEARCH/NERV & MENT DIS
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-12-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7408693
• 关键词: Address; Anesthesia procedures; Arts; Brain Injuries; Caring; Clinical; Clinical Research; Collaborations; Condition; Conscious; Consciousness Disorders; Development; Diagnostic Procedure; Diffusion; Dimensions; Disease; Electroencephalography; Evaluation; Fostering; Functional Magnetic Resonance Imaging; Future; Generalized Epilepsy; Goals; Knowledge; Magnetic Resonance Imaging; Magnetoencephalography; Minimally Conscious States; Neurobiology; Neurologist; Neurons; Neurosciences; Patient Care; Patients; Population; Positron-Emission Tomography; Process; Psyche structure; Psychiatrist; Publications; Recovery; Research; Research Personnel; Scientific Advances and Accomplishments; Shapes; Staging; Techniques; Therapeutic; Time; Update; awake; base; career; improved; interest; member; neuroimaging; programs; psychobiology; research clinical testing; symposium

DESCRIPTION (provided by applicant): Advances in neuroimaging and neuroscience hold significant promise for improving the understanding of disorders of consciousness arising from severe brain injuries. This meeting will focus on bringing together basic neuroscientists and investigators focusing on neuroimaging studies of patients with disorders of consciousness in different clinical settings. The goal of this meeting is to advance knowledge of diagnostic methods and experimental therapeutic strategies as well as identify challenges for professionals engaged in the study of these patient populations. The program will begin with an update and discussion of the neuronal mechanisms underlying the awake conscious state. Recent neuroimaging findings from patients in the vegetative state (VS) and minimally conscious state (MCS), and related conditions such as generalized epilepsies and anesthesia will then be discussed. Presentations will canvass several techniques including positron emission tomography, functional magnetic resonance imaging, quantitative electroencephalography and magnetoencephalography, and diffusion tensor magnetic resonance imaging studies. The relatively long time courses of recovery following severe brain injury emphasize the need to develop markers for identifying patients who may harbor further potential for meaningful recovery. Introduction of neuroimaging into the clinical evaluation process, however, will require a close collaboration among investigators and clinicians to organize the emerging knowledge so that scientific advances may help shape the care of patients. To this end clinicians engaged in each stage of evaluation of patients with disorders of consciousness will address the goals of neuroimaging in their clinical context. Finally, the broad and critical ethical dimensions of this evolving research will be discussed. The goal of this meeting will be to provide a state of the art view of advances in knowledge of diagnostic methods and experimental therapeutic strategies as well as identify challenges for professionals engaged in the study of these patient populations. Attendees will gain an understanding of the importance of studies of consciousness arising from severe brain injuries that are emerging as relevant for clinical research and treatment. Through publication of the proceedings information critical to future research and clinical care to a wider audience will be provided.

描述(由申请人提供)：神经成像和神经科学的进步为提高对严重脑损伤引起的意识障碍的理解带来了巨大的希望。这次会议的重点是聚集基础神经学家和研究人员，重点是在不同的临床环境下对意识障碍患者进行神经成像研究。本次会议的目标是促进对诊断方法和实验性治疗策略的了解，并确定从事这些患者群体研究的专业人员面临的挑战。该计划将从更新和讨论清醒意识状态背后的神经机制开始。然后将讨论植物状态(VS)和最低意识状态(MCS)患者的最新神经影像表现，以及相关情况，如全身性癫痫和麻醉。报告将介绍几种技术，包括正电子发射断层扫描、功能磁共振成像、定量脑电和磁脑成像，以及扩散张量磁共振成像研究。严重脑损伤后相对较长的康复过程强调了开发标记物的必要性，以确定哪些患者可能具有进一步有意义的康复潜力。然而，将神经成像引入临床评估过程将需要研究人员和临床医生之间的密切合作，以组织新出现的知识，以便科学进步可能有助于塑造对患者的护理。为此，参与意识障碍患者评估的每个阶段的临床医生将在他们的临床背景下解决神经成像的目标。最后，将讨论这项不断发展的研究的广泛和关键的伦理层面。本次会议的目标将是提供诊断方法和实验性治疗策略知识的最新进展的最新观点，并确定从事这些患者群体研究的专业人员面临的挑战。与会者将了解对严重脑损伤引起的意识研究的重要性，这些研究正在成为临床研究和治疗的相关内容。通过出版会议记录，将向更广泛的受众提供对未来研究和临床护理至关重要的信息。