明胶酶在小鼠模型负荷损伤后软骨降解中的作用-猫眼课题宝

明胶酶在小鼠模型负荷损伤后软骨降解中的作用

批准号：

7509016

负责人：

CHIH S CHEN

金额：

$8.46万

依托单位：

HOSPITAL FOR SPECIAL SURGERY

依托单位国家：

美国

项目类别：

财政年份：

2007

资助国家：

美国

项目状态：

已结题

起止时间：

2007-03-01 至 2008-02-28

来源：

https://reporter.nih.gov/project-details/7509016

关键词：

Accidents Acute Affect Age American Animal Model Apoptosis Cartilage Cell Death Cells Centers for Disease Control and Prevention (U.S.)Chemistry Cleaved cell Collaborations Collagen Collagen Type II Core Protein Data Degenerative polyarthritis Elevation Enzymes Epiphysial cartilage Event Feasibility Studies Fibroblasts Fourier Transform Future Gelatin Gelatinase A Gelatinase B Gelatinases Genes Histology Image Immunohistochemistry In Situ Inflammation Inflammatory Inflammatory Response Injury Interleukin-1 Interleukin-6 Interstitial Collagenase Joints Liquid substance Matrix Metalloproteinases Measurement Mechanics Mediating Microscopy Modeling Molecular Mus Necrosis Outcome Outcome Study Phenotype Physiological Population Property Proteins Proteoglycan Recombinants Rheumatoid Arthritis Role Signal Pathway Site Sports Stromelysin 1 Synovial Fluid Synovial Membrane System TNF gene TNF-alpha converting enzyme Techniques Testing Time Tissue Inhibitor of Metalloproteinase-1 Tissues Today Week X-Ray Computed Tomography aggrecan angiogenesis cell motility collagenase collagenase 3 cytokine day enzyme activity human MMP14 protein in vitro Model in vivo interest kinematics macrophage mouse model neutrophil soft tissue therapeutic target

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