An Integrated Package for the Processing and Analysis of Diffusion Tensor Imaging

用于扩散张量成像处理和分析的集成包

• 批准号: 7501194
• 负责人: Dongrong Xu
• 金额: $ 15.99万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-11 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7501194
• 关键词: Algorithms; Clinical Research; Communities; Computer software; Data; Diffusion Magnetic Resonance Imaging; Environment; Fiber; Housing; Image; Image Analysis; Imaging Device; Linux; Magnetic Resonance Imaging; Manufacturer Name; Methods; Numbers; Operating System; Paper; Performance; Physicians; Process; Public Health; Publishing; Research; Research Personnel; Running; Software Tools; Work; base; clinical application; comparison group; graphical user interface; image processing; improved; interest; microsystems; tool; user-friendly

DESCRIPTION (provided by applicant): We aim to develop and disseminate to the MRI research community an integrated software package for processing and analyzing Diffusion Tensor Imaging (DTI) data. In addition to the inclusion of some DTI tools that we have implemented based on well-established algorithms from other's work, this software package will also include several unique tools and algorithms that we have developed in-house through our own research. We have demonstrated through published papers that a number of our key tools and algorithms offer improved performance over previously available methods. This software package will allow investigators and clinicians free access to our research tools within an integrated, user-friendly format, thereby facilitating image analysis and clinical research. In addition, our software package will also provide tools for unified analyses using DTI in conjunction with structural (sMRI) data. PUBLIC HEALTH RELEVANCE: This proposed project an integrated software package for the processing and analysis of Diffusion Tensor Imaging (DTI) is to release the latest version of software resulted from our research in diffusion tensor imaging. This package will allow investigators and physicians free access to our work to facilitate their research and clinical applications.

描述（由申请人提供）：我们的目标是开发并向 MRI 研究界传播一个用于处理和分析扩散张量成像 (DTI) 数据的集成软件包。除了包含一些我们根据其他人的工作中成熟的算法实现的 DTI 工具外，该软件包还将包含我们通过自己的研究在内部开发的几种独特的工具和算法。我们通过发表的论文证明，我们的许多关键工具和算法比以前可用的方法提供了更高的性能。该软件包将允许研究人员和临床医生以集成的、用户友好的格式免费访问我们的研究工具，从而促进图像分析和临床研究。此外，我们的软件包还将提供使用 DTI 结合结构 (sMRI) 数据进行统一分析的工具。公共健康相关性：该拟议项目是一个用于处理和分析扩散张量成像（DTI）的集成软件包，旨在发​​布我们在扩散张量成像研究中产生的最新版本的软件。该软件包将允许研究人员和医生免费访问我们的工作，以促进他们的研究和临床应用。

项目成果

Evaluation of non-local means based denoising filters for diffusion kurtosis imaging using a new phantom.

使用新体模进行扩散峰度成像的基于非局部均值的去噪滤波器的评估

• DOI: 10.1371/journal.pone.0116986
• 发表时间: 2015
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Zhou MX;Yan X;Xie HB;Zheng H;Xu D;Yang G
• 通讯作者: Yang G