Identification and chracterization of host cell receptors for influenza A viruses

甲型流感病毒宿主细胞受体的鉴定和表征

• 批准号: nhmrc : 1017158
• 负责人: Miss Wyching Ng
• 金额: $ 6.16万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-chracterization-host-influenza-viruses/109831
• 关键词: Identification; chracterization; host; cell; receptors

Following inhalation, influenza virus infects cells of the immune system and epithelial cells lining the airways. Currently, it is not clear how influenza virus attaches to and infects these cells. This project will use new ways to identify receptors for influenza virus on human epithelial cells and immune cells. The ultimate identification of these receptors would have important implications for the development of new drugs to treat influenza virus infections.

吸入后，流感病毒感染免疫系统细胞和呼吸道上皮细胞。目前还不清楚流感病毒是如何附着并感染这些细胞的。本项目将采用新的方法鉴定人类上皮细胞和免疫细胞上的流感病毒受体。这些受体的最终鉴定将对开发治疗流感病毒感染的新药具有重要意义。