CHIMERA TOOLS FOR THE VIRUS PARTICLE EXPLORER WEB SITE

用于病毒颗粒探索者网站的嵌合体工具

• 批准号: 7723542
• 负责人: THOMAS GODDARD
• 金额: $ 1.54万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723542
• 关键词: Biomedical Technology; Capsid; Cataloging; Catalogs; Chimera organism; Color; Computer Retrieval of Information on Scientific Projects Database; Depth; Development; Electron Microscopy; Funding; Grant; Image; Imagery; Institution; Internet; Maps; National Center for Research Resources; Proteins; Research; Research Personnel; Resources; Shapes; Site; Source; United States National Institutes of Health; Virion; Virus; density; molecular modeling; multi-scale modeling; structural biology; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project develops Chimera visualization capabilities needed for the Virus Particle Explorer (VIPERdb) web site (http://viperdb.scripps.edu). The VIPERdb web site catalogs molecular models and electron microscopy density maps of icosahedral virus particles. It presents images of virus capsids showing the shapes and packing of proteins, the icosahedral lattice, and radially depth coloring. The Chimera package is used to produce some of these images using commands or scripts developed specifically for the web site. This project involves the ongoing development of these Chimera commands and scripts. The VIPERdb web site is a project of an NCRR Biomedical Technology Research Resource called Multiscale Modeling Tools for Structural Biology (MMTSB) directed by Charles Brooks.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目开发病毒粒子浏览器(VIPERdb)网站(http://viperdb.scripps.edu).)所需的嵌合体可视化能力VIPERdb网站列出了二十面体病毒粒子的分子模型和电子显微镜密度图。它展示了病毒衣壳的图像，显示了蛋白质的形状和堆积，二十面体晶格，以及径向深度着色。Chimera包被用来使用专门为网站开发的命令或脚本来生成其中一些图像。该项目涉及这些嵌合体命令和脚本的持续开发。VIPERdb网站是由Charles Brooks指导的名为结构生物学多尺度建模工具(MMTSB)的NCRR生物医学技术研究资源的项目。