HUMAN PROTEOME FOLDING PROJECT (HPF)

人类蛋白质组折叠项目（HPF）

• 批准号: 7723735
• 负责人: RICHARD A BONNEAU
• 金额: $ 0.93万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723735
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Computers; Disease; Funding; Grant; Human; Institution; Learning; Protein Structure Databases; Proteins; Proteome; Research; Research Personnel; Resources; Scientist; Shapes; Source; United States National Institutes of Health; Work; protein function

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Human Proteome Folding Project will use the computer power of millions of computers to predict the shape of Human proteins for which researchers currently know little. From this shape scientists hope to learn about the function of these proteins, as the shape of proteins is inherently related to how they function in our bodies. This database of protein structures and putative functions will let scientists take the next steps understanding how diseases that involve these proteins work and ultimately how to cure them.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 人类蛋白质组折叠项目将利用数百万台计算机的计算能力来预测目前研究人员知之甚少的人类蛋白质的形状。科学家希望从这种形状中了解这些蛋白质的功能，因为蛋白质的形状本质上与它们在我们体内的功能有关。这个蛋白质结构和假定功能的数据库将使科学家能够采取下一步行动，了解涉及这些蛋白质的疾病如何发挥作用以及最终如何治愈它们。