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HUMAN PROTEOME FOLDING PROJECT (HPF)

HUMAN PROTEOME FOLDING PROJECT (HPF)
人类蛋白质组折叠项目(HPF)
批准号:
8171349
负责人:
RICHARD A BONNEAU
金额:
$5.65万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-01 至 2011-08-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者(PI)可能从另一个NIH来源获得主要资金, 因此可以在其他CRISP条目中表示。列出的机构是 中心,不一定是研究者的机构。 人类蛋白质组折叠计划将利用数百万台计算机的计算能力来预测研究人员目前所知甚少的人类蛋白质的形状。科学家希望通过这种形状了解这些蛋白质的功能,因为蛋白质的形状与它们在我们体内的功能有着内在的联系。这个蛋白质结构和推定功能的数据库将使科学家们采取下一步措施,了解涉及这些蛋白质的疾病如何工作,并最终如何治愈它们。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Human Proteome Folding Project will use the computer power of millions of computers to predict the shape of Human proteins for which researchers currently know little. From this shape scientists hope to learn about the function of these proteins, as the shape of proteins is inherently related to how they function in our bodies. This database of protein structures and putative functions will let scientists take the next steps understanding how diseases that involve these proteins work and ultimately how to cure them.
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Integrating spatial multi-omics and clinical covariates to identify mechanisms of disease in ALS-FTD
  • 批准号:
    10034901
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2020
  • 负责人:
    RICHARD A BONNEAU
  • 依托单位:
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  • 批准号:
    10478845
  • 项目类别:
  • 资助金额:
    $57.17万
  • 财政年份:
    2018
  • 负责人:
    RICHARD A BONNEAU
  • 依托单位:
Modeling Gene Regulatory Networks for Early Cardiopharyngeal Development
  • 批准号:
    10237291
  • 项目类别:
  • 资助金额:
    $58.19万
  • 财政年份:
    2018
  • 负责人:
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  • 依托单位:
A network model of the gut host-microbe ecosystem in Inflammatory Bowel Disease
海外基金