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HUMAN PROTEOME FOLDING PROJECT (HPF)

HUMAN PROTEOME FOLDING PROJECT (HPF)
人类蛋白质组折叠项目(HPF)
批准号:
8171349
负责人:
RICHARD A BONNEAU
金额:
$5.65万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-09-01 至 2011-08-31

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 人类蛋白质组折叠项目将利用数百万台计算机的计算机能力来预测人类蛋白质的形状,目前研究人员对此知之甚少。科学家们希望从这种形状中了解这些蛋白质的功能,因为蛋白质的形状与它们在我们体内的功能有着内在的联系。这个蛋白质结构和假定功能的数据库将让科学家采取下一步行动,了解涉及这些蛋白质的疾病是如何起作用的,并最终如何治愈它们。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Human Proteome Folding Project will use the computer power of millions of computers to predict the shape of Human proteins for which researchers currently know little. From this shape scientists hope to learn about the function of these proteins, as the shape of proteins is inherently related to how they function in our bodies. This database of protein structures and putative functions will let scientists take the next steps understanding how diseases that involve these proteins work and ultimately how to cure them.
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Integrating spatial multi-omics and clinical covariates to identify mechanisms of disease in ALS-FTD
  • 批准号:
    10034901
  • 项目类别:
  • 资助金额:
    $86.72万
  • 财政年份:
    2020
  • 负责人:
    RICHARD A BONNEAU
  • 依托单位:
Modeling Gene Regulatory Networks for Early Cardiopharyngeal Development
  • 批准号:
    10478845
  • 项目类别:
  • 资助金额:
    $57.17万
  • 财政年份:
    2018
  • 负责人:
    RICHARD A BONNEAU
  • 依托单位:
Modeling Gene Regulatory Networks for Early Cardiopharyngeal Development
  • 批准号:
    10237291
  • 项目类别:
  • 资助金额:
    $58.19万
  • 财政年份:
    2018
  • 负责人:
    RICHARD A BONNEAU
  • 依托单位:
A network model of the gut host-microbe ecosystem in Inflammatory Bowel Disease
海外基金