ANALYSIS OF YEAST MITOCHONDRIAL DNA STABILITY BY DAPI STAINING

DAPI 染色分析酵母线粒体 DNA 稳定性

• 批准号: 7723720
• 负责人: MARY-CLAIRE KING
• 金额: $ 1.95万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723720
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Funding; Genes; Goals; Grant; Inherited; Institution; Mitochondria; Protein Isoforms; Recessive Genes; Research; Research Personnel; Resources; Source; Staining method; Stains; United States National Institutes of Health; Yeasts; hearing impairment; kindred; novel; positional cloning

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this project is to find and characterize genes responsible for hereditary hearing impairment. We have previously identified DFNA15 as POU4F3, DFNB30 as MYO3A, and DFNB28 as a novel isoform of TARA. In the next cycle of this project, our goals include identification of genes for recessive and dominant hearing loss, with or without syndromic features, by positional cloning in extended kindreds.

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