CILIARY ORGANIZATION IN PHOTORECEPTOR AND COCHLEAR HAIR CELLS

光感受器和耳蜗毛细胞中的纤毛组织

• 批准号: 7722453
• 负责人: David Collin Williams
• 金额: $ 0.2万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7722453
• 关键词: 3-Dimensional; Cilia; Cochlea; Computer Retrieval of Information on Scientific Projects Database; Disease; Funding; Grant; Hair Cells; Hearing Impaired Persons; Indium; Inherited; Institution; Photoreceptors; Research; Research Personnel; Resources; Retina; Role; Sensory; Source; Structure; United States National Institutes of Health; Usher Syndrome

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Photoreceptors of the retina and hair cells of the cochlea are have very specialized structures (which provide adaptations for their specialized sensory roles). A common key element in their organization concerns a cilium. We propose to study the 3-D organization of the photoreceptor and hair cell cilia, especially in relation to Usher syndrome, an inherited deaf-blindness disorder.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 视网膜的感光器和耳蜗的毛细胞具有非常特殊的结构（为其特殊的感觉作用提供适应）。 他们的组织中一个共同的关键元素是纤毛。 我们建议研究光感受器和毛细胞纤毛的 3D 组织，特别是与亚瑟综合征（一种遗传性聋盲症）的关系。