CILIARY ORGANIZATION IN PHOTORECEPTOR AND COCHLEAR HAIR CELLS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 视网膜的光感受器和耳蜗的毛细胞具有非常专门的结构（这为它们专门的感觉作用提供了适应）。 它们组织中的一个共同的关键元素是纤毛。 我们建议研究感光细胞和毛细胞纤毛的三维组织，特别是与Usher综合征，一种遗传性眼盲症。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Photoreceptors of the retina and hair cells of the cochlea are have very specialized structures (which provide adaptations for their specialized sensory roles). A common key element in their organization concerns a cilium. We propose to study the 3-D organization of the photoreceptor and hair cell cilia, especially in relation to Usher syndrome, an inherited deaf-blindness disorder.