CORE--LABORATORY ANIMAL CARE RESOURCE

实验动物资源（LAR）主要由RPCI的研究人员负责实验动物的护理和使用，并获得同行评审的资金。2002年6月，该资源获得了国际实验动物护理评估和认证协会（AAALAC International）的全面认证。资源提供专业化畜牧业；兽医医疗；动物卫生监测；诊断实验室设施；研究技术服务和资源，包括基因定义小鼠；外科手术程序和技术人员；和教师培训，以支持150多个研究所动物护理和使用委员会批准的动物使用协议。其他服务包括兔的多克隆抗体生产，小鼠的杂交瘤腹水生产和收集，以及近亲繁殖和免疫缺陷啮齿动物的生产。每日牲畜存栏21000头，

The Laboratory Animal Resource (LAR) is responsible for laboratory animal care and use primarily by investigators at RPCI with peer-reviewed funding. In June 2002, the Resource was granted full accreditation by the Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). The Resource provides specialized animal husbandry; veterinary medical care; animal health surveillance; diagnostic laboratory facilities; research technical services and resources including genetically defined mice; a surgical program and technician; and faculty training in support of more than 150 Institute Animal Care and Use Committee-approved animal use protocols. Additional services include polyclonal antibody production in rabbits, hybridoma ascites production and collection in mice, and inbred and immune-deficient rodent production. Daily animal inventories of 21,000, include a variety of rodent species, rabbits, dogs and occasionally farm animals. The Resource Director is a New York State licensed veterinarian who has been trained in pathology (PhD) and is Board-Certified in Laboratory Animal Medicine (ACLAM). Fifteen members of the technical staff are certified through the Certification and Registry Board of the American Association for Laboratory Animal Science (AALAS). The Laboratory Animal Resource is located in the four-story 39,000 nsf vivarium within the Medical Research Complex (MRC), which opened in 1998. Additional newly renovated space is available in the Cancer Cell Center, for a total of approximately 47,000 nsf. Laboratories for work with gene knockout and transgenic technologies in mice are immediately adjacent to animal holding rooms. Continued support through the CCSG will permit the Resource to provide a standard of care and use that meets or exceeds applicable state and federal standards, maintain full AAALAC International accreditation, and furnish investigators with a comprehensive program for safe, appropriate and cost-effective research animal use.