Wireless power transmission to implanted devices

向植入设备进行无线电力传输

• 批准号: 7805102
• 负责人: Leon Radziemski
• 金额: $ 28.93万
• 依托单位: PIEZO ENERGY TECHNOLOGIES, LLC
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2011-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7805102
• 关键词: Acute; Advanced Development; Analgesics; Area; Biocompatible; Biocompatible Materials; Centers for Disease Control and Prevention (U.S.); Cessation of life; Charge; Contracts; Defibrillators; Development; Devices; Diagnostic; Distress; Effectiveness; Electromagnetics; Electronics; Ensure; Evaluation; Exposure to; Family suidae; Fostering; Foundations; Frequencies; Funding; Goals; Government; Growth; Guidelines; Health; Health Care Costs; Healthcare; Healthcare Industry; Heating; Histocompatibility Testing; Human; Implant; In Vitro; Infection; Intellectual Property; Lead; Legal patent; Length of Stay; Letters; Licensing; Longevity; Magnetic Resonance Imaging; Manufacturer Name; Marketing; Measurement; Medical Device; Metals; Methods; Mission; Modeling; Monitor; Muscle; Operative Surgical Procedures; Output; Pacemakers; Pain; Pain management; Parkinson Disease; Patients; Persons; Pharyngeal structure; Phase; Physics; Power Sources; Procedures; Production; Proliferating; Public Health; Radio; Regulation; Research Design; Safety; Schedule; Seeds; Site; Staging; Stomach; Symptoms; System; Techniques; Technology; Temperature; Temperature Sense; Testing; Therapeutic; Time; TimeLine; Tissues; Ultrasonography; United States National Institutes of Health; Urinary tract; Weight; Wireless Technology; awake; base; chemotherapy; compliance behavior; cost; design; design and construction; heart function; human tissue; implantable device; implanted sensor; improved; in vivo; innovation; interest; miniaturize; nano; next generation; novel; operation; pressure; prototype; public health relevance; research and development; research study; safety study; sensor; simulation; transmission process

DESCRIPTION (provided by applicant): A clear need exists for the development of advanced power ources and recharging options for implanted electro-medical devices. The useful lifetime of most implants is constrained by the longevity of the power source. When an implanted primary (non-rechargeable) battery has discharged to a predetermined threshold, surgery must be scheduled to replace the battery or the entire device, at considerable cost, patient distress, and about a 2% chance of infection. Implantable devices that might use rechargeable batteries include a growing variety of neurostimulators to counteract Parkinson's symptoms, for chemotherapy, to electrically stimulate the stomach, throat, urinary tract and other muscles, to deliver pain medication, and for implanted pressure and temperature sensors whose use will proliferate quickly. All of these applications place demands on electrical power within the body. A novel new method for recharging secondary batteries can overcome some of the difficulties of the present method, which includes MRI incompatibility. The wireless power transmission technology being developed is based on well known principles of ultrasound, which is know for its safety in diagnostic applications. The potential advantages include smaller transmitters and receivers, elimination of electromagnetic interference and heating of metal parts, and transmission of power to deeper sites in the body. The latter will drive new applications. Our principal goals and specific aims are to demonstrate its ultimate capabilities in vivo, facilitate more rapid recharging thus fostering patient compliance, comply with FDA safety regulations, and move the technology forward to the prototype stage, ready to be made into a useful product. We will do this by increasing its power delivery, showing that any temperature rise is kept within FDA guidelines, developing alignment and cooling techniques, and constructing small and inexpensive components. This technology will support the NIH mission, advancing its goals to improve human health and reduce health care costs by: 1) alleviating the distress, pain, and complications by reducing battery replacement operations, 2) increasing functionality of the implant by providing more power for diagnostic output or burst mode operation, 3) improving patient compliance, and 4) reducing the number of expensive operations that replace batteries and other components. PUBLIC HEALTH RELEVANCE: This new wireless recharging technique will result in increased longevity and capability of implanted batteries and will advance several public health goals by: 1) alleviating distress, pain, complications and cost by reducing the number of battery replacement operations, 2) increasing functionality of the implant by providing more power for diagnostic output or burst mode operation, 3) improving patient compliance.

描述（由申请人提供）：明确需要开发用于植入电子医疗设备的先进电源和充电选项。大多数植入物的使用寿命受到电源寿命的限制。当植入的初级（不可充电）电池放电到预定的阈值时，必须安排手术更换电池或整个设备，这需要相当大的成本、患者的痛苦和大约2%的感染机会。可能使用可充电电池的植入式设备包括各种各样的神经刺激器，用来抵消帕金森症的症状，用于化疗，电刺激胃、喉咙、泌尿道和其他肌肉，传递止痛药，以及用于植入式压力和温度传感器，其用途将迅速扩大。所有这些应用都需要体内的电力。一种新的二次电池充电方法可以克服现有方法的一些困难，包括MRI不兼容。正在开发的无线电力传输技术是基于众所周知的超声原理，超声在诊断应用中以其安全性而闻名。潜在的优势包括更小的发射器和接收器，消除电磁干扰和金属部件的加热，以及将能量传输到身体更深的部位。后者将推动新的应用。我们的主要目标和具体目标是展示其在体内的最终能力，促进更快的充电，从而促进患者的依从性，符合FDA安全法规，并将技术推进到原型阶段，准备制成有用的产品。我们将通过增加其功率输出来实现这一目标，表明任何温度上升都保持在FDA的指导方针内，开发校准和冷却技术，以及构建小型和廉价的组件。这项技术将支持美国国立卫生研究院的使命，推进其改善人类健康和降低医疗保健成本的目标：1)通过减少电池更换手术来减轻痛苦，疼痛和并发症，2)通过为诊断输出或突发模式操作提供更多功率来增加植入物的功能，3)提高患者的依从性，4)减少更换电池和其他组件的昂贵手术次数。