Administrative core

行政核心将为整个提案提供组织骨干，协调 项目与核心之间的内部互动以及与NHLBI通过 以下是具体目标： 具体任务1：促进项目1-4与核心A和B之间的沟通，并协助所有项目 在手稿准备中。&gt； 具体任务2：提供威斯康星大学、研究所和项目之间的沟通机制 评论者。 具体任务3：通过与UW IRB的互动，为所有项目和核心提供监管支持 以及食品和药物管理局。 行政核心将通过组织与本提案中的所有项目和核心进行互动， 每月内部项目评审会议的通知和会议纪要的分发。行政部门 CORE将监督科目应收率，以确保每个项目都能够满足其要求的样本 尺码。该核心将负责编写年度进展报告并向研究所提交 并将根据需要组织外部审查，核心将与FDA合作，以获得调查 新药申请建议使用抗IL-5抗体。行政核心将协助所有 合作编写手稿和为数据演示准备幻灯片的项目。

The administrative core will provide the organizational backbone for the overall proposal, coordinating the internal interactions between Projects and Cores as well as the external communication with NHLBI through the following specific aims: Specific Task 1: To facilitate communication between Projects 1-4 and Cores A and B and assist all projects in manuscript preparation. > Specific Task 2: To provide mechanisms for communication between UW, the Institute and project reviewers. Specific Task 3: To provide regulatory support to all projects and cores through interactions with the UW IRB and the FDA. The administrative core will interact with all projects and cores in this proposal through organization, notification and meeting minute distribution of monthly internal project review meetings. The administrative core will oversee the rate of subject accrual to assure that each project is able to meet its required sample size. The core will be responsible for preparation and submission of annual progress reports to the Institute and will organize external reviews as needed and the core will work with the FDA to obtain an Investigational New Drug application for the proposed use of anti-IL-5 antibody. The administrative core will assist all projects in collaborative manuscript preparation and preparation of slides for data presentations.