ADMINISTRATIVE CORE, OVERALL APPROACH

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 A.具体目标 长Meharry转化研究中心（MeTRC）的长期目标是建立一个临床和转化健康差异研究的国家模型。MeTRC将协同NCRR支持的Meharry的几项正在进行的研究计划，包括少数民族机构研究中心，艾滋病健康差异研究中心，妇女健康研究中心，临床研究中心和临床研究教育和职业发展计划。在Meharry研究企业的特别优势的基础上，MeTRC的重点将是传染病，包括艾滋病毒/艾滋病和妇女健康。将建立一个综合的转化研究计划，涵盖基础，基础研究，应用，参与涉及临床研究。短我们的长期目标是改变Meharry转化研究的能力和基础设施。具体目标是：1.建立一个行政基础设施，以促进综合和创新的转化和临床研究计划（MeTRC）的开发和维护; 2.开发技术和支持基础设施，以维持综合转化和临床研究计划; 3.建立一个过程，以促进RCTR教师和工作人员之间的协作互动和沟通，以维持和发展创新临床和转化研究的综合计划; 4.建立基础，转化和临床研究的管道，将维持和发展的MeTRC计划; 5.通过建立新的参与者和临床互动资源（PCIR），显著增强转化和临床研究的基础设施; 6.发展多学科的培训和职业生涯利用RCTR的基础设施，计划和教师进行临床和转化研究的发展计划; 7.参与并加强在范德比尔特下创建的现有计划Meharry CTSA重点合作伙伴关系，以促进社区的进程和伙伴关系基于临床和转化研究;以及 8.制定并实施自我计划短期评估长期和长期RCTR目标，包括项目活动的实施和跟踪。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A. Specific Aims The longterm goal of the Meharry Translational Research Center (MeTRC) is to establish a national model for clinical and translational health disparities research. MeTRC will synergize several ongoing research initiatives at Meharry supported by NCRR, including Research Center in Minority Institutions, Center for AIDS Health Disparities Research, Center for Women¿s Health Research, Clinical Research Center, and Clinical Research Education and Career Development Program. Building on particular strengths of the research enterprise at Meharry, the focus of MeTRC will be on infectious disease, including HIV/AIDS, and women¿s health. An integrated program of translational research will be established that spans basic, fundamental research to applied, participantinvolved clinical studies. The shortterm goal is to transform the capacity and infrastructure for translational research at Meharry. The specific aims are: 1. Develop an administrative infrastructure that will facilitate development and maintenance of an integrated and innovative translational and clinical research program (MeTRC); 2. Develop a technical and support infrastructure that will sustain a program of integrated translational and clinical research; 3. Establish a process to facilitate the collaborative interactions and communication between RCTR faculty and staff needed to sustain and grow an integrated program of innovative clinical and translational research; 4. Establish a pipeline of basic, translational, and clinical research that will sustain and develop the MeTRC program; 5. Significantly enhance the infrastructure for translational and clinical research by establishing a new Participant and Clinical Interactions Resource (PCIR); 6. Develop a multidisciplinary training and careerdevelopment program in clinical and translational research that takes advantage of the infrastructure, programs, and faculty of RCTR; 7. Engage and enhance an existing program created under the VanderbiltMeharry CTSA Focused Partnership to facilitate processes and partnerships in communitybased clinical and translational research; and 8. Develop and implement a plan for selfevaluation of shortterm and longterm RCTR goals including implementation and tracking of program activities.