ADMINISTRATIVE CORE, OVERALL APPROACH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 A.具体目标 梅哈里翻译研究中心(METRC)的长期目标是为临床和翻译健康差异研究建立一个全国性的模型。Metrc将协同Meharry正在进行的几项研究活动，包括少数民族机构研究中心、艾滋病健康差距研究中心、S妇女健康研究中心、临床研究中心以及临床研究教育和职业发展计划。在梅哈里研究机构独特优势的基础上，Metrc的重点将放在传染病，包括艾滋病毒/艾滋病和妇女健康方面。将建立一个涵盖基础、基础研究到应用型、参与性临床研究的综合转化型研究计划。短期目标是改变Meharry的翻译研究能力和基础设施。具体目标是：1.发展行政基础设施，以促进综合和创新的转化和临床研究计划(METRC)的开发和维护； 2.开发技术和支持基础设施，以支持翻译和临床研究的综合计划； 3.建立一个流程，以促进RCTR教职员工之间的协作互动和沟通，以支持和发展创新临床和转化研究的综合计划； 4.建立基础、转译和临床研究管道，以支持和发展Metrc计划； 5.通过建立新的参与者和临床互动资源(PCIR)，显著增强翻译和临床研究的基础设施； 6.开发临床和转化性研究中的多学科培训和职业发展计划，利用RCTR的基础设施、计划和教师； 7.参与和加强在Vanderbilt Meharry CTSA Focted Partnership下创建的现有计划，以促进社区临床和转化研究中的进程和伙伴关系；以及 8.制定和执行一项自我评估短期和长期区域协调机制目标的计划，包括方案活动的执行和跟踪。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A. Specific Aims The longterm goal of the Meharry Translational Research Center (MeTRC) is to establish a national model for clinical and translational health disparities research. MeTRC will synergize several ongoing research initiatives at Meharry supported by NCRR, including Research Center in Minority Institutions, Center for AIDS Health Disparities Research, Center for Women¿s Health Research, Clinical Research Center, and Clinical Research Education and Career Development Program. Building on particular strengths of the research enterprise at Meharry, the focus of MeTRC will be on infectious disease, including HIV/AIDS, and women¿s health. An integrated program of translational research will be established that spans basic, fundamental research to applied, participantinvolved clinical studies. The shortterm goal is to transform the capacity and infrastructure for translational research at Meharry. The specific aims are: 1. Develop an administrative infrastructure that will facilitate development and maintenance of an integrated and innovative translational and clinical research program (MeTRC); 2. Develop a technical and support infrastructure that will sustain a program of integrated translational and clinical research; 3. Establish a process to facilitate the collaborative interactions and communication between RCTR faculty and staff needed to sustain and grow an integrated program of innovative clinical and translational research; 4. Establish a pipeline of basic, translational, and clinical research that will sustain and develop the MeTRC program; 5. Significantly enhance the infrastructure for translational and clinical research by establishing a new Participant and Clinical Interactions Resource (PCIR); 6. Develop a multidisciplinary training and careerdevelopment program in clinical and translational research that takes advantage of the infrastructure, programs, and faculty of RCTR; 7. Engage and enhance an existing program created under the VanderbiltMeharry CTSA Focused Partnership to facilitate processes and partnerships in communitybased clinical and translational research; and 8. Develop and implement a plan for selfevaluation of shortterm and longterm RCTR goals including implementation and tracking of program activities.