Characterizing the load of driver and passenger mutations in cancer

表征癌症中驾驶员和乘客突变的负荷

• 批准号: 7826005
• 负责人: Leonid A Mirny
• 金额: $ 33.77万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-23 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7826005
• 关键词: Accounting; Achievement; Affect; Antineoplastic Agents; Bioinformatics; Buffers; Cancer Model; Cell Separation; Cells; Cereals; Cessation of life; Complex; Data; Development; Environment; Evolution; Extinction (Psychology); Family; Frequencies; Genes; Genetic; Genetic Load; Genomics; Growth; Heat shock proteins; Heterogeneity; Individual; Knowledge; Late Effects; Lead; Malignant Neoplasms; Measurement; Mediating; Methods; Modeling; Molecular Chaperones; Mutation; Nutrient; Organism; Physics; Plant Roots; Population; Population Genetics; Probability; Process; Proteins; Recording of previous events; Resources; Role; Seminal; Somatic Mutation; Statistical Mechanics; Structure; Study models; Subjects Selections; System; Techniques; Testing; Therapeutic; Time; Work; base; cancer cell; cancer genomics; cancer stem cell; cancer therapy; cell growth; cell transformation; fitness; gain of function mutation; inhibitor/antagonist; mutant; neoplastic; novel strategies; overexpression; research study; sample fixation; simulation; theories; tumor; tumor progression; tumorigenesis