课题基金 / 基金详情

TARGETS OF A MECHANISM-BASED PROBE AGAINST CYSTEINE PROTEASES

TARGETS OF A MECHANISM-BASED PROBE AGAINST CYSTEINE PROTEASES
基于机制的半胱氨酸蛋白酶探针的靶标
批准号:
7954134
负责人:
Tom Muir
金额:
$0.12万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-03-01 至 2010-02-28

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Using LC-MS/MS, we have identified the target of a mechanism-based probe against cysteine proteases upregulated during apopotosis as Cathepsin B, implicating its activity in cell death.
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Project 3: Mechanisms of Methyltransferase Dysregulation by Oncohistones
  • 批准号:
    10024845
  • 项目类别:
  • 资助金额:
    $27.1万
  • 财政年份:
    2015
  • 负责人:
    Tom Muir
  • 依托单位:
Project 3: Mechanisms of Methyltransferase Dysregulation by Oncohistones
  • 批准号:
    10269906
  • 项目类别:
  • 资助金额:
    $21.13万
  • 财政年份:
    2015
  • 负责人:
    Tom Muir
  • 依托单位:
Development and Applications of 'Designer Chromatin'
  • 批准号:
    9060364
  • 项目类别:
  • 资助金额:
    $30.17万
  • 财政年份:
    2013
  • 负责人:
    Tom Muir
  • 依托单位:
Development and Applications of 'Designer Chromatin'
  • 批准号:
    8556589
  • 项目类别:
  • 资助金额:
    $29.77万
  • 财政年份:
    2013
  • 负责人:
    Tom Muir
  • 依托单位:
国内基金
海外基金
炎性反应中巨噬细胞激活诱导死亡(activation-induced cell death,AICD)的机理研究
  • 批准号:
    30330260
  • 项目类别:
    重点项目
  • 资助金额:
    105.0万元
  • 批准年份:
    2003
  • 负责人:
    顾军
  • 依托单位: