FAST PHOTOCHEMICAL OXIDATION OF BETA LACTOGLOBULIN AND DECTIN-1

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究使用β乳球蛋白（BLG），因为它是已知的一种 一种快速折叠的蛋白质，在氧化时会展开。 如果FPOP是 适当淬火，BLG在氧化态之间的分布应 用Poisson分布建模。 如果展开发生在 氧化的时间尺度，那么分布应该表现出非泊松 一个蛋白质的连续氧化的概率不是 与其先前的氧化无关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study uses beta lactoglobulin (BLG) because it is known to be a fast-folding protein which suffers unfolding upon oxidation. If FPOP is properly quenched, the distribution of BLG among oxidation states should be modeled by a Poisson distribution. If unfolding occurs on the timescale of oxidation, then the distribution should exhibit a non-Poisson character--the probability of a successive oxdiation of a protein is not independent of it previous oxidation.