Training in Congenital and Acquired Heart Disease

先天性和后天性心脏病培训

• 批准号: 7939687
• 负责人: TERRY S ELTON
• 金额: $ 28.42万
• 依托单位: RESEARCH INST NATIONWIDE CHILDREN'S HOSP
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7939687
• 关键词: Heart Diseases; Training

DESCRIPTION (provided by applicant): The objective of this joint Ohio State University (OSU)-Nationwide Children's Hospital (NCH) institutional T32 postdoctoral program is to provide interdisciplinary, translational and state-of-the-art research training in congenital and acquired heart disease. This plan provides a unique opportunity to focus on a continuum of congenital and acquired heart disease from birth to senescence and to compare disease mechanisms and outcomes between these diverse population. The rationale is that advances in heart disease therapy and prevention are most likely to originate from a translational research program that fosters collaboration between physician-scientists and basic scientists. To address the overall theme, we will maintain and expand ongoing efforts to provide an academic environment to cultivate true 'bidirectional' translational research, so that significant clinical problems identified by our clinician scientists can be addressed in the laboratory, and key findings at the bench can be rapidly translated to larger animal studies and eventually back to the bedside. This new application seeks 5 trainees per year for 5 years with a 2-year commitment. Fellows will be selected from MD, DVM or PhD candidates who have strong interests in cardiovascular research and are committed to careers in disease-oriented investigations. The Program Directors have a strong-track record in translational cardiovascular research and will serve as the primary directors at their respective institutions. The training plan design consists of formal academic courses, seminars and journal clubs to provide trainees with an overview of heart disease and an in-depth cardiac research orientation. Trainees will participate in a tailor-made "survival skills" course comprised of various modules and workshops related to professional development. Each trainee will perform independent research projects in a mentor's laboratory. The research areas encompassed by the 20 extramurally funded basic- and clinical-science mentors and 22 participating faculty are represented by their individual affiliations with The Heart Center at NCH and The Davis Heart and Lung Institute at OSU. A cross-institution, web-based system will be used to perform trainee and mentor evaluations.

描述（由申请人提供）： 俄亥俄州立大学 (OSU)-全国儿童医院 (NCH) 联合机构 T32 博士后项目的目标是提供先天性和后天性心脏病方面的跨学科、转化性和最先进的研究培训。该计划提供了一个独特的机会来关注从出生到衰老的一系列先天性和后天性心脏病，并比较这些不同人群之间的疾病机制和结果。其基本原理是，心脏病治疗和预防方面的进步最有可能源自促进医师科学家和基础科学家之间合作的转化研究计划。为了解决总体主题，我们将保持并扩大持续的努力，提供一个学术环境来培养真正的“双向”转化研究，以便我们的临床科学家发现的重大临床问题可以在实验室得到解决，实验室的关键发现可以迅速转化为更大规模的动物研究，并最终回到临床。 这项新申请每年寻求 5 名实习生，为期 5 年，承诺期为 2 年。研究员将从对心血管研究有浓厚兴趣并致力于以疾病为导向的研究领域的医学博士、医学博士或博士生中选拔。项目主任在转化心血管研究方面拥有良好的记录，并将担任各自机构的主要主任。培训计划设计包括正式的学术课程、研讨会和期刊俱乐部，为学员提供心脏病的概述和深入的心脏研究方向。学员将参加量身定制的“生存技能”课程，该课程由与专业发展相关的各种模块和研讨会组成。每位学员将在导师的实验室中进行独立的研究项目。 20 名校外资助的基础和临床科学导师以及 22 名参与的教师所涵盖的研究领域由他们与 NCH 心脏中心和俄勒冈州立大学戴维斯心肺研究所的个人隶属关系代表。将使用跨机构、基于网络的系统对学员和导师进行评估。