Research Training in Cardiovascular and Pulmonary Diseases

心血管和肺部疾病研究培训

• 批准号: 7837718
• 负责人: S. Jamal Mustafa
• 金额: $ 31.54万
• 依托单位: WEST VIRGINIA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7837718
• 关键词: Cardiovascular system; Lung diseases; Research Training

Description (provided by applicant): This predoctoral training grant will support the multidisciplinary research training of graduate students for careers as independent investigators conducting research in cardiovascular and/or pulmonary diseases. Faculty advisors are investigators trained in various disciplines including: Physiology, Pharmacology, Biochemistry, Cell Biology, Neurobiology, Microbiology, Immunology, Exercise Science, Genetics, Molecular Biology, Internal Medicine, Cardiology and Pulmonology. Training faculty also include established scientists at the National Institute for Occupational Safety & Health (NIOSH), known for its research on inflammation and lung diseases. NIOSH is a research division of the CDC immediately adjacent to the School of Medicine. Most training faculty are members of either the (1) Center for Cardiovascular Research or (2) Center for Respiratory Biology & Lung Disease Research. The initial period of predoctoral training will emphasize courses which include Cell Biology, Biochemistry, Physiology, Molecular Biology, Statistics and Genomic Sciences as well as training in Scientific Integrity & Ethics. This first year of graduate work is organized as an integrated, core curriculum coupled with advanced literature-based graduate elective modules in the 2nd semester, which provides a solid foundation for advanced graduate courses and research. Students select a doctoral dissertation advisor by the end of their first year, based on laboratory research rotations. Thereafter, students pursue research under the supervision of their mentor, in addition to taking selective advanced graduate courses, attending seminars, participating in journal clubs, writing their PhD thesis proposals and presenting data at national meetings. Areas of research training include endothelial cell biology, inflammation induced vascular injury, microvascular physiology, cardiac pathobiology, airway and vascular reactivity, lung epithelial pathology, vascular smooth muscle biology, gene expression and lipids, ischemia-reperfusion, reactive oxygen radicals, cell signaling pathways, vascular remodeling, and angiogenesis, to name a few. Disease relevance of trainee projects are numerous; eg. coronary ischemia, asthma, pulmonary edema, hypertension, cardiac failure, intestinal vascular inflammation, pulmonary fibrosis, peripheral vascular disease, etc. Our interactive research environment, enhanced by Interdisciplinary Research Centers provides an ideal setting for cross fertilization of ideas, constructive criticism, and training of both Ph.D., and M.D./Ph.D. students for careers as investigators.

描述（由申请人提供）：这项培训前培训补助金将支持研究生的多学科研究培训，作为职业生涯的多学科研究培训，作为从事心血管和/或肺部疾病研究的独立研究人员。教职顾问是在各种学科中接受培训的研究人员，包括：生理学，药理学，生物化学，细胞生物学，神经生物学，微生物学，免疫学，运动科学，遗传学，分子生物学，内科，心脏病学和肺病学。培训学院还包括美国国家职业安全与健康研究所（NIOSH）的成熟科学家，该研究所以其炎症和肺部疾病的研究而闻名。 NIOSH是疾病预防控制中心的一个研究部，紧邻医学院。大多数培训学院是（1）心血管研究中心的成员，或（2）呼吸生物学和肺部疾病研究中心。术前训练的最初时期将强调课程，包括细胞生物学，生物化学，生理学，分子生物学，统计学和基因组科学以及科学完整性和伦理学的培训。研究生工作的第一年是在第二学期中组织的综合核心课程以及基于先进文学的研究生选修模块，为高级研究生课程和研究提供了坚实的基础。学生根据实验室研究轮换，在第一年结束前选择博士学位论文顾问。此后，除了参加选择性的高级研究生课程，参加研讨会，参加期刊俱乐部，撰写博士学位论文建议并在国家会议上介绍数据外，学生还在导师的指导下进行研究。研究培训领域包括内皮细胞生物学，炎症诱导的血管损伤，微血管生理学，心脏病理生物学，气道和血管反应性，肺上皮病理学，肌肉平滑肌肉生物学，基因生物学表达和脂质，脂质和脂质，缺血性氧气，反应性氧气虫的命名，居住在血管造成的疾病，血管源性疾病，血管造型和血管反应，是血管疾病的疾病，且血管疾病逐渐渗透，并逐渐渗透。学员项目的疾病相关性很多；例如。冠状动脉缺血，哮喘，肺水肿，高血压，心脏衰竭，肠道血管炎症，肺纤维化，周围血管疾病等。我们的交互式研究环境，通过跨学科研究中心增强了跨学科研究中心的增强，为对思想，建设性批评和对pH.D.D.D.D.D.D.D.D.D.D.D.D.D.的理想设置提供了理想的环境。从事调查人员职业的学生。