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MRC Centre for Synaptic Plasticity

MRC Centre for Synaptic Plasticity
MRC 突触可塑性中心
批准号:
G0601841-E01/1
负责人:
Graham Collingridge
金额:
$215.21万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2008
资助国家:
英国
项目状态:
已结题
起止时间:
2008 至 --

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中文摘要
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英文摘要
The work of the MRC Centre for Synaptic Plasticity is aimed at obtaining a fuller understanding of how synapses work. Information is stored in our brains by alterations in the efficiency of communication at synapses and the MRC Centre is interested in understanding the molecular processes involved in this plasticity. Thus synaptic plasticity is critical for the correct wiring of the brain during development and enables learning and memory to occur throughout life. Pathological alterations in these mechanisms are likely to contribute to neurological and psychiatric disease. We work to understand the processes that underlie these plasticity mechanisms and how they relate to learning and memory.The MRC Centre for Synaptic Plasticity is strongly committed to the public understanding of science. Indeed, its Director is a founder member of the European DANA Alliance for the Brain. MRC Centre scientists present public lectures, such as at the British Association, give talks in local schools and at open days, and communicate with the press on topical issues. The MRC Centre will continue to strongly support such activities. Members of the Centre also collaborate closely with Bristol Neuroscience (BN) in their public engagement activities, including providing and manning displays at events such as the biennial ?Science Alive? event (Bristol), Bioscience Kids (Glasgow) and Science in the Gardens (Sheffield). One researcher within the MRC Centre has been made a Fellow of the Researchers in Residence Scheme and is currently doing a placement with a local secondary school.
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Molecular mechanisms of long-term Depression in the hippocampus
  • 批准号:
    MR/K023098/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $247.28万
  • 财政年份:
    2013
  • 负责人:
    Graham Collingridge
  • 依托单位:
Role of the JAK/STAT pathway in LTD
  • 批准号:
    BB/K019899/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $64.77万
  • 财政年份:
    2013
  • 负责人:
    Graham Collingridge
  • 依托单位:
The signalling pathways involved in NMDA receptor-dependent LTD
  • 批准号:
    BB/H006451/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $51.92万
  • 财政年份:
    2010
  • 负责人:
    Graham Collingridge
  • 依托单位:
Mechanisms of NMDA receptor-dependent LTP and LTD in the hippocampus.
  • 批准号:
    G0601813/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $238.32万
  • 财政年份:
    2008
  • 负责人:
    Graham Collingridge
  • 依托单位:
海外基金