CTSA INFRASTRUCTURE FOR AIDS RESEARCH

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 加州大学戴维斯分校（UC Davis）正在提议建立一个临床和转化科学中心（CISC），该中心将通过以下三项关键资产将我们的医学研究企业转变为一个高效的“开放式”临床和转化研究学术之家：1）我们作为一所赠地大学的长期承诺，为地理上分散和种族多样的人提供服务 内陆和北方加州的人口拥有世界上最广泛和最广泛的电信计划之一所支持的医疗保健系统; 2）加州大学戴维斯分校的合作文化，它拥有全国最广泛和跨学科的生命科学环境之一，和3）一个既定的CSTC试点机构-加州大学戴维斯分校临床研究调查者服务计划（CRISP）作为临床和转化研究以及教师培训和职业发展的物理家园。CRISP是一个非常重要的CTSC试验场，在那里，我们探索了许多CTSA障碍并测试了解决方案，通过CRISP，我们完成了规划 在CTSC阶段。在加州大学戴维斯分校CTSC的组织结构中，相当注意创建一个组织：1）响应和熟悉调查人员; 2）灵活; 3）与大学领导层，参与学术单位和社区有很好的联系; 4）专注于 减少障碍，促进将研究成果转化为医疗实践。主要特点是：教育计划侧重于“团队科学”;在加州大学戴维斯分校学院和中心的广泛合作;引入催化剂功能，如合作研究促进者和翻译 博士后奖学金;通过远程技术传播;灵活使用资源进行以病人为导向的研究;以及强调信任和尊重的社区参与计划。CTSC由两名共同主要研究者领导，Berglund MD，PhD，（P.I.）和Joseph MD，PhD（co-P.I.），由董事和联席董事团队监督9个CTSC计划中的每一个的支持，以及一个全面的委员会结构，旨在与机构领导，教师，学员和社区牢固地锚CTSC。加州大学戴维斯分校CTSC将通过精心设计的合作计划实施，并通过持续的评估和纠正指导活动。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of California, Davis (UC Davis) is proposing to create a Clinical and Translational Science Center (CISC) which will transform our medical research enterprise into a highly jeffective "open" academic home for clinical and translational research by building on three key assets: 1) Our long-standing commitment as a land-grant university to serve the geographically disperse and ethnically diverse populations of inland and Northern California with a health care system enabled by one of the broadest and most extensive telecommunications programs in the world; 2) The collaborative culture of UC Davis, which has one of the most extensive and interdisciplinary life science environments in the country, and 3) An established CSTC pilot facility - the UC Davis Clinical Research Investigator Services Program (CRISP) that serves as the physical home for clinical and translational research and for faculty training and career development. CRISP is a fundamentally important CTSC testing ground, where many perceived CTSA barriers have been explored and solutions tested, and through CRISP, we have completed the planning phase for the CTSC. In the organizational structure of the UC Davis CTSC, considerable attention is paid to create an organization that is: 1) responsive and familiar to investigators; 2) flexible; 3) well linked to university leadership, to participating academic units, and to the community; and 4) focused on the goal of reducing barriers and facilitating the translation of research gains into medical practice. Key features are: Education program focused on "team science"; Extensive collaborations across UC Davis colleges and centers; Introduction of catalyst functions such as Collaborative Research Facilitators and translational postdoctoral fellowships; Dissemination through tele-technology; Flexible use of resources for patientoriented research; and a Community engagement program emphasizing trust and respect. The CTSC is under the leadership of two co-Principal Investigators, Drs. Berglund MD, PhD, (P.I.) and Joseph MD, PhD (co-P.I.), supported by a team of Directors and co-Directors overseeing each of the 9 CTSC programs, and a comprehensive committee structure, designed to firmly anchor the CTSC with institutional leadership, faculty, trainees and the community. The UC Davis CTSC will be implemented through a carefully designed, collaborative plan, and the activity will be guided through continuous evaluations and corrections.