An investigation of women's experiences of an IVF egg sharing scheme for somatic cell nuclear transfer research

女性体细胞核移植研究 IVF 卵子共享计划经历的调查

• 批准号: G0701109/1
• 负责人: Erica Haimes
• 金额: $ 37.75万
• 依托单位: Newcastle University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2008
• 资助国家: 英国
• 起止时间: 2008 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0701109%2F1
• 关键词: investigation; women; experiences; IVF; egg

This study will investigate the experiences of women donating eggs for stem cell research. In exchange for their eggs, women will receive cheaper IVF treatment.Stem cell research promises much for the treatment of diseases. Such treatments will be improved if the problem of a patient rejecting stem cells from an unrelated donor can be solved. A technique called somatic cell nuclear transfer (SCNT: also known as ‘therapeutic cloning’) will help to overcome this difficulty. More research is required to improve SCNT techniques but there is a shortage of human eggs. Therefore this ‘egg sharing’ scheme has been proposed. This scheme has been approved by the Human Fertilisation and Embryology Authority. However, concerns have been raised, including: objections to embryo experimentation; fears that therapeutic cloning will lead to reproductive cloning; views that reduced IVF fees constitute an inappropriate inducement to egg sharers; questions whether egg sharers understand the research to which they are contributing. Therefore it is vital that SCNT research is accompanied by evaluations of its potential benefits and costs. This study will provide such an evaluation and supply vital evidence to inform the deliberations and practices of policymakers, stem cell scientists, fertility clinicians, and the wider community, worldwide.

这项研究将调查女性为干细胞研究捐献卵子的经历。作为卵子的交换，女性将接受更便宜的体外受精治疗。干细胞研究对疾病的治疗大有希望。如果能够解决患者排斥来自非亲属供体的干细胞的问题，这种治疗方法将得到改进。一种称为体细胞核移植（SCNT：也称为“治疗性克隆”）的技术将有助于克服这一困难。为了改进SCNT技术，还需要进行更多的研究，但目前人类卵子短缺。因此，这个“鸡蛋共享”计划被提出。这个方案已经得到了人类受精和胚胎学管理局的批准。然而，人们也提出了一些担忧，包括：反对胚胎实验；担心治疗性克隆会导致生殖性克隆；认为降低试管婴儿费用是对卵子分享者的不适当引诱；质疑分蛋者是否理解他们所参与的研究。因此，SCNT研究必须伴随着对其潜在收益和成本的评估。这项研究将提供这样的评估，并提供重要的证据，为决策者、干细胞科学家、生育临床医生和全世界更广泛的社区的审议和实践提供信息。