The Development of Sustained Attention in Infants

婴儿持续注意力的发展

• 批准号: 7846290
• 负责人: JOHN E RICHARDS
• 金额: $ 3.8万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2009-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7846290
• 关键词: Adult; Affect; Age; Area; Attention; Auditory; Brain; Cerebral cortex; Characteristics; Child; Complex; Cues; Development; Electroencephalography; Emerging Technologies; Event-Related Potentials; Eye Movements; Head; Heart Rate; Individual; Infant; Magnetic Resonance Imaging; Measures; Mechanics; Modeling; Nature; Nursery Schools; Participant; Pattern; Peripheral; Phase; Preschool Child; Procedures; Psychophysiology; Research; Role; Saccades; Scalp structure; Source; Stimulus; Structure; System; Techniques; Television; Time; United States National Institutes of Health; Visual; Work; base; density; directed attention; memory recognition; mind control; relating to nervous system; research study; response

DESCRIPTION (provided by applicant): The objectives are to study the development of sustained attention in young infants and to relate development in sustained attention to concurrent heart rate (HR) changes and brain activity (EEG, ERP). The specific aims are: 1) To study sustained, subject-controlled attention in infants from 14 to 26 weeks of age, and to study the effect of attention on eye movements to complex / dynamic peripheral stimuli; 2) To study the cortical basis of planned eye movements and recognition memory in young infants with high- density EEG and ERP, and to study the effect of attention on infant saccade planning and infant, recognition memory; 3) To develop realistic models of cortical source analysis using infant anatomical MRI, to accurately identify brain areas that control the effect of sustained attention on eye movements, attention, and recognition memory. This research examines the patterns of attention found in normal children, relates those attentiontics on the timing and characteristics of eye movements in the early part of this age range (14 to 26 weeks). Experiment 2 examines infant planned eye movements using a spatial cueing procedure and Experiment 3 examines the relation between attention and recognition memory. These two studies will use "high-density" EEG recording to infer cortical sources of attention-directed eye movement control. Models of cortical source analysis using realistic models of infants' brain and head will be developed to examine the cortical sources of ERP in these two experiments. It is predicted that 1) age changes in sustained attention will interact with development changes in eye movements to affect attention-directed eye movements; 2) planned eye movements and recognition memory will show developmental changes that are related to changes in brain activity; 3) emerging technologies for inferring cortical activity using high-density EEG recording should reveal the cortical sources involved in the control of infant planned saccades and recognition memory.

描述（由申请人提供）：目标是研究小婴儿持续注意力的发展，并将持续注意力的发展与并发心率（HR）变化和大脑活动（EEG、ERP）联系起来。具体目标是： 1）研究14至26周龄婴儿的持续、受试者控制的注意力，并研究注意力对眼动对复杂/动态外周刺激的影响； 2）高密度脑电图和ERP研究小婴儿计划性眼动和识别记忆的皮质基础，研究注意力对婴儿扫视计划和婴儿识别记忆的影响； 3) 使用婴儿解剖 MRI 开发皮质源分析的真实模型，以准确识别控制持续注意力对眼球运动、注意力和识别记忆影响的大脑区域。这项研究检查了正常儿童的注意力模式，并将这些注意力与该年龄段早期（14 至 26 周）眼球运动的时间和特征联系起来。实验 2 使用空间提示程序检查婴儿计划的眼球运动，实验 3 检查注意力和识别记忆之间的关系。这两项研究将使用“高密度”脑电图记录来推断注意力导向眼球运动控制的皮层来源。将开发使用婴儿大脑和头部的真实模型的皮质源分析模型，以检查这两个实验中 ERP 的皮质源。据预测，1）持续注意力的年龄变化会与眼动的发育变化相互作用，从而影响注意力导向的眼动； 2）有计划的眼球运动和识别记忆会表现出与大脑活动变化相关的发育变化； 3）使用高密度脑电图记录推断皮质活动的新兴技术应该揭示参与控制婴儿计划性眼跳和识别记忆的皮质源。