Intergenerational Determinants of Youth Smoking Trajectories

描述(申请人提供)：这项研究的长期目标是了解与烟草相关的健康风险的代际传播。它侧重于母婴孕期吸烟(SDP)的作用。研究有四个具体目标：1)描述青少年吸烟轨迹；2a)评估SDP与青少年吸烟轨迹之间直接关系的强度；2b)评估间接影响在儿童和青春期期间通过子女的行为问题或母亲的持续吸烟而中介作用的强度；3)将SDP对青少年吸烟轨迹的影响与其他个人、同伴和家庭的吸烟决定因素分开。这项研究开发了一个完整的一生-生命过程框架，提供了关于母亲吸烟行为与其子女吸烟行为之间联系的社会和生物机制的四个假说。方法论方法扩展和评估了以前文献中的发现。数据来自1979年全国青年纵向调查(NLSY79)和NLSY79儿童和青年成人纵向调查(NLSY79-CyA)。NLSY79和NLSY79-CyA一起组成了一项具有人口代表性的两年一次的调查，从1986年到2004年的18年间对母亲和她们所生的所有孩子进行了调查。这些调查提供了丰富的代际数据，内容涉及产妇和青少年的物质使用、儿童认知和行为发展以及儿童、家庭、同龄人和邻里层面的烟草使用的社会和生物决定因素。我们使用自回归潜在轨迹方法，使我们能够检验在不同年龄测量的决定因素之间的因果关系，同时也使用潜在变量方法来修正对社会和发展路径中中介作用的低估。 公共卫生相关性：这项研究调查了早期生活、儿童和青春期的代际路径如何影响成熟青少年和年轻人的健康和社会福祉的烟草相关决定因素。

DESCRIPTION (provided by applicant): The long-term objective of this study is to understand intergenerational transmission of tobacco-related health risks. It focuses on the role of maternal-child exposure to maternal smoking during pregnancy (SDP). There are four specific aims: 1) characterize youth smoking trajectories; 2a) evaluate the strength of direct relationships between SDP and youth smoking trajectories; 2b) evaluate the strength of indirect influences that entail mediation during childhood and adolescence by either the offspring's behavior problems or the mother's continued smoking; 3) disentangle the influence of SDP on youth smoking trajectories from other individual, peer, and family determinants of smoking. The study develops an integrated lifespan-life course framework informing four hypotheses about the social and biological mechanisms linking mothers' smoking behavior with that of their children. The methodological approach extends and evaluates findings from previous literature. Data come from the National Longitudinal Survey of Youth 1979 (NLSY79) and the Children & Young Adults of the NLSY79 (NLSY79-CYA). Together the NLSY79 and NLSY79-CYA comprise a population-representative, biennial survey of mothers and all children born to them over an 18 year period from 1986-2004. These surveys offer rich, intergenerational data on maternal and youth substance use, child cognitive and behavioral development, and the social and biological determinants of tobacco-use at the child, family, peer and neighborhood level. We employ an autoregressive latent trajectory approach that allows us to examine causal relationships among determinants measured at different ages, while also using latent variable methods to correct for the underestimation of mediation through social and developmental pathways. PUBLIC HEALTH RELEVANCE: This study examines how intergenerational pathways in early life, childhood and adolescence shape tobacco related determinants of the health and social wellbeing of maturing adolescents and young adults.