Identifying maternal and fetal genetic determinants of infant birthweight and their relationship to offspring cardiometabolic risk

确定婴儿出生体重的母体和胎儿遗传决定因素及其与后代心脏代谢风险的关系

• 批准号: nhmrc : GNT1157714
• 金额: $ 36.8万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-maternal-fetal-cardiometabolic-risk/1378999
• 关键词: Identifying; maternal; fetal; genetic; determinants

Children who are born of low birthweight are at increased risk of diseases like diabetes and high blood pressure in later life. This project aims to perform the world’s largest genetic study of birthweight, determine whether the genes that affect birthweight arise from the influence of the mother’s or offspring genome, and then use this information to investigate the relationship between birthweight and future risk of diseases like diabetes and high blood pressure.

出生时体重过轻的儿童在以后的生活中患糖尿病和高血压等疾病的风险增加。该项目旨在进行世界上最大的出生体重遗传研究，确定影响出生体重的基因是否来自母亲或后代基因组的影响，然后利用这些信息调查出生体重与未来糖尿病和高血压等疾病风险之间的关系。