Identifying new therapeutic targets for preventing the induction and progression of COPD

确定预防 COPD 诱发和进展的新治疗靶点

• 批准号: nhmrc : 1003593
• 负责人: Prof Peter Wark
• 金额: $ 43.3万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-new-therapeutic-progression-copd/108950
• 关键词: Identifying; new; therapeutic; targets; preventing

Smoking leads to lung inflammation that causes emphysema, which is a major health problem in Australia. Once induced there is a progressive decline in health, which continues even after stopping smoking. There are no treatments that halt this decline. Recently small genes have been discovered that control inflammation. We may be able to control these small genes and stop the induction and progression of emphysema. This project may lead to a completely new way of preventing and treating emphysema.

吸烟导致肺部炎症，导致肺气肿，这是澳大利亚的一个主要健康问题。一旦吸烟，健康状况就会逐渐下降，即使在戒烟后也会继续下降。没有任何治疗方法可以阻止这种下降。最近发现了控制炎症的小基因。我们也许能够控制这些小基因，阻止肺气肿的诱发和发展。这个项目可能会带来一种预防和治疗肺气肿的全新方法。