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中文摘要
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简介(申请人提供):海洋生物实验室开设胚胎学课程已有113多年的历史,在美国发育生物学家的培养中发挥了重要作用。该课程培养博士后和博士后学生,在独特的物理和智力环境中从事发育生物学的研究工作,这在美国其他地方是不能复制的。胚胎学课程包括一系列的正式讲座、非正式研讨会、扩展讨论和在夏季为期六周的密集实验室研究经验。该课程的学生是从国际申请者中挑选出来的,他们致力于发育生物学领域的教学和研究事业。传统上,每年班级的一些学生后来都会进入国际发育生物学研究界的领导职位。教学人员是该领域的资深科学家,他们中的一些人担任本课程的讲师和研究模块的负责人,另一些人将就个别主题进行讲座和领导讨论。课程由三个单元组成,每个单元大约两周的时间。每个单元平均配备3至4名驻地讲师,外加同等数量的外部讲师。随着外地重要事态发展的变化,单元的主题每年都在变化。本课程向学生介绍大量的陆地和海洋胚胎,包括线虫、果蝇、海鞘、海胆、两栖动物、斑马鱼、雏鸟和老鼠。方法包括当前的分子生物学技术、胚胎操作、显微注射和微操作、显微镜和计算机增强成像技术,以及一些免疫化学和原位杂交方法。学生被要求在设备齐全的研究环境中,在经验丰富的研究教师和助理的指导下,制定和检验假设。为了支持这门课程,海洋生物图书馆提供了独特的学习环境、实验室和支持设施、动物收藏设施和优秀的研究图书馆。
英文摘要
DESCRIPTION (provided by applicant): For over 113 years, the Marine Biological Laboratory has offered the Embryology Course, which has played an important role in the training of American developmental biologists. The course trains pre- and postdoctoral students for research careers in developmental biology in a unique physical and intellectual environment, not duplicated elsewhere in the nation. The Embryology Course consists of a series of formal lectures, informal seminars, extended discussions, and intensive laboratory research experience delivered over a six-week period in the summer. Course students are selected who are committed to teaching and research careers in the field of developmental biology, and are chosen from an international applicant pool. Traditionally, a number of the students from each year's class later move into positions of leadership in the international developmental biology research community. The teaching faculty members are senior scientists in the field, some of whom serve as instructors and lead research modules in the course, and others will give lectures and lead discussion on individual topics. The course consists of three modules, each of which is about two weeks long. Each module is staffed by an average of three to four resident instructors plus a comparable number of outside lecturers. The themes of the modules change from year to year as important developments in the field change. The course introduces students to a large number of terrestrial and marine embryos including C. elegans, Drosophila, ascidians, sea urchins, amphibians, zebrafish, chick, and mouse. Approaches include current molecular biological technologies, embryonic manipulation, microinjection and micromanipulation, microscopy and computer enhanced imaging technologies, and a number of immunochemical and in situ hybridization approaches. Students are challenged to formulate and test hypotheses in a well-equipped research environment and under the guidance of experienced research faculty and assistants. In support of the course, the Marine Biological Library provides a unique learning environment, laboratory and support facilities, an animal collection facility, and an excellent research library.
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Project III - Modeling meningomyelocele alleles and response to folic acid diet in mouse
Project III - Modeling meningomyelocele alleles and response to folic acid diet in mouse
Project III - Modeling meningomyelocele alleles and response to folic acid diet in mouse
Non-coding RNA regulation of early neural development
  • 批准号:
    10062529
  • 项目类别:
  • 资助金额:
    $56.75万
  • 财政年份:
    2019
  • 负责人:
    Lee A. Niswander
  • 依托单位:
海外基金