Identifying new genes involved in the development of epilepsy

识别参与癫痫发展的新基因

• 批准号: nhmrc : GNT1070668
• 负责人: Dr Sarah Heron
• 金额: $ 36.34万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-new-genes-development-epilepsy/1344992
• 关键词: Identifying; new; genes; involved; development

Epilepsy affects approximately 2% of the population at some stage of their lives. We have recently identified two new genes involved in the development of a type of epilepsy known as ADNFLE. We aim to identify further epilepsy genes by sequencing ADNFLE patients who do not yet have identified mutations. We also aim to identify the genes interacting with the genes we have identified, increasing our understanding of the cellular networks involved in the development of epilepsy.

大约 2% 的人口在生命的某个阶段患有癫痫症。我们最近发现了两个与 ADNFLE 类型癫痫的发生有关的新基因。我们的目标是通过对尚未确定突变的 ADNFLE 患者进行测序来进一步确定癫痫基因。我们还旨在识别与我们已识别的基因相互作用的基因，增加我们对癫痫发展中涉及的细胞网络的理解。