NON-HUMAN PRIMATE REAGENT RESOURCE

非人灵长类试剂资源

• 批准号: 7950539
• 负责人: KEITH A. REIMANN
• 金额: $ 420.45万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-29 至 2014-09-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7950539
• 关键词: NON; HUMAN; PRIMATE; REAGENT; RESOURCE

The goal of the Nonhuman Primate (NHP) Reagent Resource is to facilitate and accelerate immunological research in immune-mediated and infectious diseases using this valuable animal model through the development, evaluation, production and distribution of key immunologic reagents to the NHP research community. Reagents covered under this contract include those to 1) monitor or determine the dynamics and parameters of immune responses in vitro and in vivo, 2) deplete select immune cells in vivo, and 3) therapeutically modulate the immune response in vivo. The reagents developed by this contract are used in nonhuman primate models to study immune-mediated diseases, infectious diseases, and transplantation.

非人灵长类(NHP)试剂资源的目标是利用这一有价值的动物模型，通过开发、评估、生产关键免疫试剂并将其分发给NHP研究社区，促进和加速免疫介导性疾病和传染病的免疫学研究。本合同涵盖的试剂包括：1)监测或确定体外和体内免疫反应的动力学和参数；2)消耗体内选定的免疫细胞；3)治疗调节体内的免疫反应。该合同开发的试剂用于非人类灵长类动物模型，以研究免疫介导性疾病、传染病和移植。