COMMON INSTRUMENTATION AREA AND TECHNICAL SUPPORT UNIT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 CIAS在提供必要的基础设施方面发挥了关键作用，这些基础设施是开发强大的研究项目所必需的，否则这些项目在这所小型大学是不可能实现的。特别是，CIAS是一个核心区域，拥有主要设备和集中式细胞培养设施。CIAS促进设备共享，集中维护设备，并为所有项目的设备提供维修。目前，UCC有两名技术员要满足科学界的需求：一名电子技术员和一名机械车间操作员。对于该机构的研究的维持和未来的发展，CIAS仍然是不可或缺的。在这项建议中，我们要求拨款以继续保存和提升RCMI最初资助的现有设施和资源，包括共用仪器、电子设备车间和机械车间。此外，我们要求提供资金，通过租用实验室空间的拖车来暂时解决研究实验室空间有限的问题，同时我们确保为UCC永久增加一个资金。自五年前获得资助以来，我们为两名新的调查人员提供了实验室空间，并更换了过时的设备，包括一个闪烁计数器、一台冷藏台式离心机和一台高速冷藏离心机。此外，我们还开发和实施了设施监测系统，以持续监测保温箱、冰箱和冰柜的状态。该系统的三个阶段已经完全完成。这些设备监测CIAS设备、地下室的储存库冰柜和其他设备，以及微生物学、免疫学和药理学系的设备。监测生理学和解剖学部门的系统的第四阶段正在进行中，预计在未来两个月内完成。以上详述的要素构成了我们维持、加强和扩大科学研究基础设施的计划的基础。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. CIAS has had a pivotal role in providing the infrastructure necessary to develop strong research programs that would otherwise be impossible at this small university. In particular, CIAS is a core area housing major equipment and the centralized cell culture facility. CIAS fosters equipment sharing, centralizes maintenance of equipment and provides repair for the equipment of all the projects. There are currently two technicians to see to the needs of the scientific community at UCC; An electronics technician and a machine shop operator handyman. The CIAS continues to be indispensable for the maintenance and future development of research at this institution. In this proposal, we requested funding to continue to conserve and upgrade the existing facilities and resources initially funded by RCMI including the common instrumentation, the electronics shop and the machine shop. In addition, we requested money to provide a temporary solution to the problem of limitations of space for research laboratories by renting trailers for laboratory space while we secure funding for a permanent addition to the UCC. Since receiving funding 5 years ago, we have provided laboratory space for two new investigators and have replaced obsolete equipment including a scintillation counter, a refrigerated table top centrifuge and a high speed refrigerated centrifuge. Moreover, we have developed and implemented a facilities monitoring system to continuously monitor the status of incubators, refrigerators and freezers. Three phases of this system are completely finished. These monitor the CIAS equipment, the repository freezers and other equipment housed in the basement, and the equipment of the Departments of Microbiology and Immunology and Pharmacology. The fourth phase of the system to monitor the Departments of Physiology and Anatomy is underway and expected to be completed in the next two months. The elements detailed above form the basis of our plan to maintain, fortify and expand our infrastructure for scientific research.