COMMON INSTRUMENTATION AREA AND TECHNICAL SUPPORT UNIT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 研究中心，而研究中心不一定是研究者所在的机构。 通用仪器区和服务单位（CIAS）的目标是为UCC的研究人员提供开发和执行高质量研究项目所需的主要设备和服务。 有超过25名非常活跃的调查人员（其中许多人的项目由RCMI、SNRP、MBRS、DOD、INBRE和CNS资助），他们严重依赖这一核心设施。 CIAS容纳仪器，如高速和超离心机，凝胶文件系统，闪烁计数器，伽马计数器，水蒸馏器和制冰机，这些仪器在大学的其他地方都没有，因此，CIAS促进设备共享和集中维护设备。此外，CIAS为新的和建立的研究者提供了一个共同的细胞培养室，这些研究者在自己的实验室中没有设施，并作为研究者的备用设施，配备细胞培养罩和孵育器。在CIAS的保护下，有一个机械车间和一个电子车间。这些研讨会由两名技术人员维护，他们致力于满足UCC科学界的需求。在本建议书中，我们要求拨款，以继续保存和提升最初由RCMI资助的现有设施和资源，包括通用仪器、电子车间和机械车间。 以下具体目标构成了我们维护、加强和扩大科学研究基础设施计划的基础。 目标#1：为UCC教师提供必要的设备，成为富有成效的研究人员。 目标#2：更新现有工具。 目标#3：开发设备校准服务 目标#4：继续电子车间和精密机械/木工车间部件。 目标5：继续实施设施监测系统。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Common Instrumentation Area and Services Unit (CIAS) has the objective of providing the investigators at UCC with the major equipment and services that are needed for developing and executing high quality research projects. There are over 25 very active investigators (many with projects funded by RCMI, SNRP, MBRS, DOD, INBRE and CNS) who rely heavily on this core facility. The CIAS houses instrumentation such as high speed and ultra-centrifuges, a gel documentation system, a scintillation counter, a gamma counter, water distillers and ice machines that are not available elsewhere at the University and therefore, the CIAS fosters equipment sharing and centralizes maintenance of equipment. In addition, the CIAS provides a common cell culture room for new and established investigators who do not have the facilities in their own laboratories and as a backup facility for investigators with cell culture hoods and incubators. Under the umbrella of the CIAS, there is a machine shop and an electronics workshop. These workshops are maintained by two technicians who are dedicated to fulfilling the needs of the scientific community at UCC. In this proposal, we request funding to continue to conserve and upgrade the existing facilities and resources initially funded by RCMI including the common instrumentation, the electronics shop and the machine shop. The following specific aims form the basis of our plan to maintain, fortify and expand our infrastructure for scientific research. Aim #1: to provide UCC faculty with the necessary equipment to be productive researchers. Aim #2: to update the existing instrumentation. Aim #3: to develop an equipment calibration service Aim #4: to continue the electronics workshop and precision machine/carpentry shop components. Aim #5: to continue the Facilities Monitoring System (FMS).