Neuroeconomics of Drug Addiction

描述（由申请人提供）：新兴的跨学科领域神经经济学利用经济学的计算严谨性和现代生物学的技术进步来推进决策科学的发现。由于决策的病态是成瘾的特有症状——它们在成瘾的发展中起着因果作用，它们加剧了成瘾的生物和社会后果，并损害了补救和治疗——美国国立卫生研究院已经认识到神经经济学是解决这一重要社会问题的基础。在此，我们建议成立一个国家药物滥用研究所（NIDA） P30核心中心，将杜克大学的两个机构优势领域——神经经济学/认知神经科学和跨学科成瘾研究——联合起来，支持聘请两名新教员，每名教员都与杜克大学脑科学研究所（DIBS）和一个学术部门合作。杜克大学在这两个领域都是国际公认的领导者，但他们的集体优势还没有被带到成瘾决策的核心问题上。这些领域有几个现有的机构实力领域，包括神经经济学研究中心（CNS）、认知神经科学中心（CCN）、nida支持的转化预防研究中心（TPRC）、杜克大学尼古丁和戒烟研究中心（CNSCR）、福库商学院，以及神经生物学、精神病学、心理学和神经科学院系内强大的行为神经科学小组。尽管有这些优势，但根本差距依然存在。拟议中的核心中心将填补杜克大学决策研究界的重要空白，将带来重要和前沿的研究能力，并将加强杜克大学作为这一重要研究领域的领先机构之一的地位。它将为神经科学本科专业和更广泛的研究生培训带来新的教学能力。最后，它将为DIBS与神经科学的社会相关应用提供一个重要的新链接，这与杜克大学的“知识在社会的Sen/ice”的战略目标是一致的。NIDA P30核心中心将为杜克大学提供杠杆作用，立即填补这些空白，并通过聘请两名新教员来促进这些不同群体的整合，这两名教员分别带来了弥合杜克大学当前神经经济学和成瘾研究的新专业知识。

DESCRIPTION (provided by applicant): The nascent interdisciplinary field of Neuroeconomics harnesses the computational rigor of economics and the technological advances of modern biology to advance discovery in the decision sciences. Since pathologies of decision making are endemic to addiction-they serve a causal role in its development, they exacerbate the biological and social consequences of the disorder, and they impair remediation and treatment ~ the National Institutes of Health has recognized Neuroeconomics as fundamental to solving this important societal problem. Here we propose a National Institute of Drug Abuse (NIDA) P30 Core Center uniting two areas of institutional strength at Duke, Neuroeconomics/Cognitive Neuroscience and Interdisciplinary Addiction Research, to support hiring two new faculty, each in partnership with the Duke Institute for Brain Sciences (DIBS) and an academic department: Duke is an internationally recognized leader in both of these fields, yet their collective strengths have not yet been brought to bear on core problems of decision making in addiction. There are several areas of existing institutional strength in these areas that include the Center for Neuroeconomic Studies (CNS), the Center for Cognitive Neuroscience (CCN), the NIDA-supported Translational Prevention Research Center (TPRC), the Duke Center for Nicotine and Smoking Cessation Research (CNSCR), The Fuqua School of Business, and the strong behavioral neuroscience groups within the Departments of Neurobiology, Psychiatry, and Psychology and Neuroscience. Despite these strengths, fundamental gaps remain. The proposed Core Center will fill important gaps in the Duke decision-making research community, will bring important and cutting-edge research competencies, and will strengthen Duke's position as one of the leading institutions in this important research area. It will bring new teaching capabilities to the undergraduate neuroscience major and to graduate training more broadly. Finally, it will provide an important new link for DIBS to socially relevant applications for neuroscience, consistent with Duke's strategic goal of "Knowledge in the Sen/ice of Society". A NIDA P30 Core Center will give Duke the leverage to immediately fill these gaps and catalyze integration of these disparate groups by hiring two new faculties that each brings new expertise bridging current Neuroeconomics and Addiction research at Duke.