UCSF Pediatric Device Consortium

描述(由申请人提供)： 加州大学旧金山分校的临床创新小组每周三上午8点在儿科外科/胎儿治疗中心会议室开会。该小组包括来自儿科外科(迈克尔·哈里森及同事)、加州大学伯克利分校/加州大学旧金山分校联合生物工程计划(Shuvo Roy)和生物医学测试机构(Jenni Buckley)的研究人员，以及来自旧金山州立大学和加州海事学院的机械和电气工程师、研究生、研究员、生物医学系统工程师、矫形师以及各种设备开发商、原型制造商、制造商和创新者，他们将临床问题和解决方案带到每周会议上。在过去的五年里，许多儿科设备已经被设计、改进、工程、原型、在动物模型中测试、在人体试验中测试、在会议上展示、出版和销售。知识产权已通过加州大学旧金山分校技术管理办公室获得保护，并授权给初创设备公司和较大的医疗设备公司。 调查人员建议将这一经过验证的生产性企业正规化为加州大学旧金山分校的儿科设备联盟，由迈克尔·哈里森(儿科外科)和舒沃·罗伊(生物工程)领导。该基础设施将支持任何对新型儿科设备有想法的研究人员，从最初的想法到营销，处于开发的任何阶段。 调查人员有许多儿科设备开发项目正在筹备中。以下是五个拟议的投资组合项目： *漏斗胸磁性微型推进器(目前正在进行人体试验) *复杂先天性心脏病新生儿维持动脉导管通畅的装置 *用于非侵入性肠道吻合的Magnamsis(目前在动物试验中) *用于脊柱侧弯和肢体延长的机器人植入物(目前处于动物试验阶段) *针对阻塞性睡眠呼吸暂停症的Magnap(原型开发和IDE)

DESCRIPTION (provided by applicant): The Clinical Innovations Group at UCSF meets every Wednesday at 8 AM in the Pediatric surgery/Fetal Treatment Center conference room. The group includes investigators from pediatric surgery (Michael Harrison and colleagues), the combined UC Berkeley/UCSF Bioengineering Program (Shuvo Roy), and the Biomedical Testing Facility (Jenni Buckley), as well as mechanical and electrical engineers from San Francisco State University and the California Maritime Academy, postgraduate students, research fellows, biomedical systems engineers, orthotists, and a wide variety of device developers, prototype makers, manufacturers, and innovators who bring their clinical problems and solutions to the weekly meeting. Over the last five years, many pediatric devices have been designed, refined, engineered, prototyped, tested in animal models, tested in human trials, presented at meetings, published, and marketed. Intellectual property has been secured through the UCSF Office of Technology Management and licensed to start-up device companies and larger medical device companies. The investigators propose to formalize this proven productive enterprise as the UCSF Pediatric Device Consortium under the leadership of Michael Harrison (Pediatric Surgery) and Shuvo Roy (Bioengineering). The infrastructure will support any investigator who has an idea for a novel pediatric device at any stage of development from initial idea to marketing. The investigators have many pediatric device development projects in the pipeline. The following are five proposed portfolio projects: * Magnetic Mini-Mover for pectus excavatum (currently in human trials) * Devices for maintaining patency of the ductus arteriosus in neonates with complex congenital heart disease * Magnamosis for non-invasive intestinal anastomosis (currently in animal trials) * Roboimplant for scoliosis and limb-lengthening (currently in animal trials) * Magnap for obstructive sleep apnea (prototype development and IDE)