LACTIC ACIDEMIA AND MITOCHONDIRAL MYOPATHY

乳酸血症和线粒体肌病

• 批准号: 7950906
• 负责人: RICHARD H HAAS
• 金额: $ 0.91万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7950906
• 关键词: Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Defect; Funding; Gluconeogenesis; Grant; Institution; Metabolism; Myopathy; Pyruvate; Pyruvates; Research; Research Personnel; Resources; Source; United States National Institutes of Health; lactic acidemia; oxidation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The lactic acidemias are heterogeneous. The project objective is to define abnormalities in metabolism, and to develop systemic approaches to therapy. Defects in pyruvate oxidation and in gluconeogenesis will be studied.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 乳酸血症是异质性的。该项目的目标是定义新陈代谢异常，并开发系统的治疗方法。丙酮酸氧化和糖异生方面的缺陷将被研究。