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LACTIC ACIDEMIA AND MITOCHONDIRAL MYOPATHY

LACTIC ACIDEMIA AND MITOCHONDIRAL MYOPATHY
乳酸血症和线粒体肌病
批准号：
7724870
负责人：
RICHARD H HAAS
金额：
$1.6万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-12-01 至 2008-11-30
来源：
https://reporter.nih.gov/project-details/7724870
关键词：
Computer Retrieval of Information on Scientific Projects DatabaseDefectFundingGluconeogenesisGrantInstitutionMetabolismMyopathyPyruvatePyruvatesResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healthlactic acidemiaoxidation

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 乳酸血症是异质性的。该项目的目标是定义新陈代谢异常，并开发系统的治疗方法。丙酮酸氧化和糖异生方面的缺陷将被研究。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The lactic acidemias are heterogeneous. The project objective is to define abnormalities in metabolism, and to develop systemic approaches to therapy. Defects in pyruvate oxidation and in gluconeogenesis will be studied.
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