UCSD VENOUS INCIDENCE STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 具体目标 1.在1600名男性和女性的多民族队列中，确定11年新静脉疾病的发病率和现有疾病的进展，这些人的静脉状况(患病率)在基线上得到了准确的确定。 2.评价静脉性疾病发病和进展的危险因素。 3.确定症状与静脉疾病的时间关系；即症状是否先于(以及随后)事件或进行性静脉疾病？ 4.a)评估生活质量的变化、伴随的事件或进行性静脉疾病，说明非静脉发病率的变化。 B)使用一种新的全面、有效的生活质量和症状指数--静脉功能不全流行病学和经济学研究

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific Aims 1. To determine the eleven-year incidence of new venous disease, and progression of existing disease, in a multi-ethnic cohort of 1600 men and women who had their venous status(prevalence) accurately determined at baseline. 2. To evaluate risk factors for incident and progressive venous disease. 3. To determine the temporal relation of symptoms to venous disease; i.e. can symptoms precede(as well as follow) incident or progressive venous disease? 4. a) to evaluate change in a quality of life, accompanying incident or progressive venous disease accounting for changes in non-venous morbidity. b) to utlize a new comprehensive, validated QOL and symptom index, the Venous Insufficiency Epidemiological and Economic Study