UCSD VENOUS INCIDENCE STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 具体目标 1.在一个由1600名男性和女性组成的多种族队列中，确定11年新发静脉疾病的发病率和现有疾病的进展，这些男性和女性在基线时准确确定了静脉状态（患病率）。 2.评价静脉疾病发生和进展的危险因素。 3.确定症状与静脉疾病的时间关系;即症状是否先于（以及随后）偶发或进行性静脉疾病？ 4. a）评估生活质量的变化，伴随的事件或进行性静脉疾病占非静脉发病率的变化。 B）采用一种新的综合性、经验证的QOL和症状指数，即静脉功能不全流行病学和经济学研究

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific Aims 1. To determine the eleven-year incidence of new venous disease, and progression of existing disease, in a multi-ethnic cohort of 1600 men and women who had their venous status(prevalence) accurately determined at baseline. 2. To evaluate risk factors for incident and progressive venous disease. 3. To determine the temporal relation of symptoms to venous disease; i.e. can symptoms precede(as well as follow) incident or progressive venous disease? 4. a) to evaluate change in a quality of life, accompanying incident or progressive venous disease accounting for changes in non-venous morbidity. b) to utlize a new comprehensive, validated QOL and symptom index, the Venous Insufficiency Epidemiological and Economic Study