A DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, MULTI-CENTER STUDY TO EVALUATE T

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是前瞻性地检验阿莱法塞特治疗严重头皮斑秃的安全性和有效性。银屑病和斑秃之间的共同特征，包括免疫学和治疗方面，表明阿法塞特已被证明是治疗银屑病的一种安全和有统计学意义的有益治疗方法，可能对斑秃具有治疗价值。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to examine prospectively the safety and efficacy of alefacept in the treatment of subjects with severe alopecia areata of the scalp. Common features between psoriasis and alopecia areata, including immunologic and thereapeutic aspects, suggests that alefacept, which has been shown to be a safe and statistically significant beneficial therapeutic modality for the treatment of psorasis, may have thereapeutic value in alopecia areata.