A DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED, MULTI-CENTER STUDY TO EVALUATE T

一项评估 T 的双盲、安慰剂对照、随机、多中心研究

• 批准号: 7951687
• 负责人: MARIA K HORDINSKY
• 金额: $ 0.04万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951687
• 关键词: Alopecia Areata; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Double-Blind Method; Funding; Grant; Immunologics; Institution; Modality; Placebo Control; Psoriasis; Randomized; Research; Research Personnel; Resources; Safety; Scalp structure; Source; Therapeutic; United States National Institutes of Health; alefacept

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to examine prospectively the safety and efficacy of alefacept in the treatment of subjects with severe alopecia areata of the scalp. Common features between psoriasis and alopecia areata, including immunologic and thereapeutic aspects, suggests that alefacept, which has been shown to be a safe and statistically significant beneficial therapeutic modality for the treatment of psorasis, may have thereapeutic value in alopecia areata.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是前瞻性地检查阿法塞治疗严重头皮斑秃的安全性和有效性。银屑病和斑秃之间的共同特征，包括免疫学和治疗方面，表明阿法西普，这已被证明是一个安全和统计学上显着的有益的治疗银屑病的治疗方式，可能有斑秃的治疗价值。