AIR POLLUTION AND CARDIAC RISK: MECHANISMS AND TIME-COURSE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项应用的主要目标是将我们对空气污染和心血管反应之间的短期相关性的基于人群的调查扩展到临床研究，即环境PM2.5(空气动力学直径为2.5微米的颗粒物)的致心律失常、血压、炎症、凝血和纤溶机制和时间进程的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this application is to extend our population-based investigations of short-term associations between air pollution and cardiovascular responses to clinical investigations of the arrhythmogenic, blood pressure, inflammatory, coagulation, and fibrinolytic mechanisms and time course of ambient PM2.5 (particles with aerodynamic diameter < 2.5 micrometers) effects.