NOVEL MULTI-MODALITY MRI & TRANSCRANIAL STIMULATION TO STUDY BRAIN CONNECTIVITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 功能磁共振成像和经颅磁刺激(TMS)的结合是非侵入性和无痛的，可以暂时扰乱局部脑区的活动。这一组合是提高对特定区域在大脑活动中的贡献的认识的初步试验。因此，在这个项目中，我们建议开发一种革命性的方法，利用BNL的4-T磁共振扫描仪，集成TMS、fMRI和DTI，从而提供关于大脑功能和连接的独特窗口。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The combination of fMRI and transcranial magnetic stimulation (TMS), which is non-invasive and painless, can transiently disrupt activity in focal brain regions. This combination was the initial trial to improve the acknowledgement about the contribution of specific areas in brain activity. Therefore, in this project we propose to develop a revolutionary methodology integrating TMS, fMRI and DTI, using BNL's 4-T MR scanner, so as to provide the unique windows on brain function and connectivity.