GENOMICS OF BRAIN STRUCTURE AND FUNCTION

脑结构和功能的基因组学

• 批准号: 7950815
• 负责人: Elena Shumay
• 金额: $ 6.44万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7950815
• 关键词: Behavioral; Blood specimen; Brain; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Consent; DNA; Data; Enrollment; Funding; Genes; Genetic; Genomics; Grant; Human; Institution; Participant; Protocols documentation; Recruitment Activity; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; Variant; base; design; genetic analysis; neuroimaging

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project aims to assess and characterize potential genetic contributions to human brain structure and function. This is an umbrella protocol and it is designed to consent subjects who are already recruited to neuroimaging protocols to provide a blood sample for genetic analysis and storage. Therefore the protocol does not have a targeted enrollment. Participants in this protocol are the subjects recruited to other protocols who agree to provide their DNA for the purpose of genomic analysis in conjunction with their neuroimaging and behavioral data derived from the original protocol for which they initially consented. This protocol was conceived based on the hypothesis that the common variations of certain genes contribute to variability in brain structure and function.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目旨在评估和表征基因对人类大脑结构和功能的潜在贡献。这是一个总括方案，旨在同意已招募到神经影像学方案的受试者提供血液样本进行遗传分析和储存。因此，方案没有目标入组。本方案中的参与者是招募到其他方案的受试者，他们同意提供其DNA用于基因组分析，并提供来自其最初同意的原始方案的神经成像和行为数据。该方案是基于这样的假设构思的：某些基因的共同变异有助于大脑结构和功能的变异。