EFFECTS OF A STEROID CHALLENGE ON GLUCOSE TOLERANCE

类固醇挑战对葡萄糖耐量的影响

• 批准号: 7951164
• 负责人: KRISTI SILVER
• 金额: $ 2.28万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951164
• 关键词: Blood Glucose; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Diabetes Mellitus; Family history of; Fasting; Funding; Grant; Institution; Kidney Transplantation; Maryland; Measurement; Measures; Medical center; Monitor; OGTT; Patients; Pharmaceutical Preparations; Prednisone; Race; Recruitment Activity; Research; Research Personnel; Resources; Risk; Source; Steroids; Transplant Recipients; Transplantation; United States National Institutes of Health; Universities; Weight; diabetic; diabetic patient; glucose tolerance; non-diabetic; sugar

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will recruit non-diabetic patients listed for renal transplantation at the University of Maryland Medical Center. The purpose of our study is to find out if we can identify kidney transplant patients who will develop diabetes after transplant by performing an oral glucose tolerance test and measuring their sugar levels before and after receiving prednisone. After transplant, subjects will be monitored to determine if they develop diabetes by both fasting blood sugar measurements and OGTTs every few months for a total of 1 year after kidney transplant. Additional patient information collected will include assessment of more traditional factors that increase diabetic risk, such as weight, medications, family history of diabetes, and race.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 这项研究将招募马里兰大学医学中心列入肾移植名单的非糖尿病患者。我们研究的目的是找出是否可以通过进行口服葡萄糖耐量测试并测量接受泼尼松前后的血糖水平来识别肾移植患者在移植后会患上糖尿病。移植后，将在肾移植后总共 1 年内，每隔几个月对受试者进行一次空腹血糖测量和 OGTT 监测，以确定他们是否患有糖尿病。收集的其他患者信息将包括对增加糖尿病风险的更传统因素的评估，例如体重、药物、糖尿病家族史和种族。