HEPATIC GLUCOSE PRODUCTION IN THE OBESE AND LEAN FELINE

肥胖和瘦猫的肝葡萄糖产生

• 批准号: 7956983
• 负责人: MARGARETHE E HOENIG
• 金额: $ 0.89万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956983
• 关键词: Carbohydrates; Computer Retrieval of Information on Scientific Projects Database; Diet; Family Felidae; Fatty acid glycerol esters; Felis catus; Food Supply; Funding; Grant; Hepatic; Institution; Insulin Resistance; Metabolism; Obesity; Physical Efforts; Research; Research Personnel; Resources; Source; United States National Institutes of Health; design; glucose production; in vivo

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. As many as 35% of all domesticated cats in the U.S. are obese, resulting primarily from an unlimited food supply that requires almost no physical effort to obtain. In cats, there is a strong correlation between BMI and insulin resistance, but little is known about hepatic fluxes in obese versus lean cats. This study was designed to determine hepatic fluxes in lean and obese cats on a high carbohydrate versus high fat diet.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 在美国，多达 35% 的家养猫肥胖，这主要是由于几乎不需要体力就能获得无限的食物供应。 在猫中，体重指数和胰岛素抵抗之间存在很强的相关性，但人们对肥胖猫和瘦猫的肝脏通量知之甚少。 本研究旨在确定高碳水化合物与高脂肪饮食的瘦猫和肥胖猫的肝通量。