HEPATIC GLUCOSE PRODUCTION IN THE OBESE AND LEAN FELINE

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。在美国，多达35%的家猫患有肥胖症，主要原因是食物供应无限，几乎不需要任何体力就能获得。在猫身上，体重指数和胰岛素抵抗之间有很强的相关性，但对肥胖猫和瘦猫的肝脏流量知之甚少。这项研究旨在确定高碳水化合物饮食和高脂肪饮食下瘦肉猫和肥胖猫的肝脏流量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. As many as 35% of all domesticated cats in the U.S. are obese, resulting primarily from an unlimited food supply that requires almost no physical effort to obtain. In cats, there is a strong correlation between BMI and insulin resistance, but little is known about hepatic fluxes in obese versus lean cats. This study was designed to determine hepatic fluxes in lean and obese cats on a high carbohydrate versus high fat diet.